{
  "abstract": "Boron trichloride (BCl₃) is highly reactive and degrades rapidly when exposed to moisture, complicating analyses, and posing safety risks under standard laboratory conditions. To address these challenges, quantitative ¹¹B nuclear magnetic resonance (qNMR) spectroscopy has been introduced as an analytical method to accurately quantitate boron trichloride in solution. This technique involves the reaction of boron trichloride with methanol to produce trimethyl borate, which is then quantified using an external standard. The preparation process allows for the reaction and sample preparation to occur in a single step within the same vial, ensuring a safe, fast, and reliable analysis. The ¹¹B qNMR method was validated, demonstrating linearity (0.02 M to 0.50 M with r = 0.9999), accuracy (recovery of 100.05%), precision (inter- and intraday), stability, and robustness. This paper highlights the effectiveness of the ¹¹B qNMR method for the accurate, reliable, fast, and safe quantification of boron trichloride in organic solvents such as dichloromethane.",
  "abstract_shown": true,
  "affiliations": [
    "Analytical Development Gilead Sciences 1021 Hayter Road Edmonton T6S 1A1 Alberta Canada gilead.com."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Daniel Van Niekerk",
      "orcid": "0009-0006-0902-6866"
    },
    {
      "affs": [
        0
      ],
      "name": "Jaspaul Tatlay",
      "orcid": "0009-0005-3180-6933"
    },
    {
      "affs": [
        0
      ],
      "name": "Hilaire V Kemami Wangun",
      "orcid": "0009-0004-6517-0411"
    },
    {
      "affs": [
        0
      ],
      "name": "Nicholas J Morehouse",
      "orcid": "0000-0003-4074-2124"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/00xc486jh128e.bib",
  "cited_by": 0,
  "doi": "10.1155/jamc/4351793",
  "fulltext_url": "https://europepmc.org/articles/PMC13695890",
  "id": "00xc486jh128e",
  "issns": [
    "2090-8865",
    "2090-8873"
  ],
  "landing_url": "https://europepmc.org/article/MED/42928886",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Organoboron and organosilicon chemistry"
    ]
  ],
  "openalex": "W7223576351",
  "pdf_url": "https://europepmc.org/articles/PMC13695890?pdf=render",
  "pmcid": "PMC13695890",
  "pmid": "42928886",
  "published": "2026-10-25",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/00xc486jh128e.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42928886",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42928886"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Organoboron and organosilicon chemistry",
      "subfield": "organic"
    }
  ],
  "title": "Quantitative Analysis of Boron Trichloride Using ¹¹B Quantitative Nuclear Magnetic Resonance Spectroscopy (qNMR).",
  "title_text": "Quantitative Analysis of Boron Trichloride Using ¹¹B Quantitative Nuclear Magnetic Resonance Spectroscopy (qNMR).",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/00xc486jh128e",
  "venue": "Journal of analytical methods in chemistry",
  "versions": []
}