{
  "abstract": "ObjectiveThis study reports a rare and life-threatening case of a giant congenital hemangioma with arteriovenous fistula in a neonate and describes its clinical management and outcomes.MethodA female neonate with a giant right forearm hemangioma with arteriovenous fistula, detected prenatally at 23 weeks, was managed by a multidisciplinary team. Postnatally, the infant developed severe pulmonary hypertension and active bleeding from the mass. Diagnosis was confirmed via computed tomography angiography and arteriography. Emergency intervention with combined embolization coil and sclerotherapy was performed, followed by oral propranolol therapy.ResultsFollowing the combined intervention and pharmacotherapy, the condition of the infant improved significantly. The severe pulmonary hypertension resolved, and the tumor size progressively reduced.ConclusionCongenital hemangioma combined with arteriovenous malformation can lead to severe, life-threatening complications. A prompt, multidisciplinary approach involving embolization, sclerotherapy, and pharmacotherapy can achieve favorable outcomes, underscoring the importance of early recognition and integrated perinatal management.",
  "abstract_shown": true,
  "affiliations": [
    "Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China",
    "Department of Pediatrics, West China Second University Hospital-Tianfu·Sichuan Provincial Children’s Hospital, Meishan City, Sichuan Province, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Peng Yue"
    },
    {
      "affs": [
        1
      ],
      "name": "Peng Yue"
    },
    {
      "affs": [
        0
      ],
      "name": "Fan Ma"
    },
    {
      "affs": [
        0
      ],
      "name": "Li Ma"
    },
    {
      "affs": [
        1
      ],
      "name": "Li Ma"
    },
    {
      "affs": [
        0
      ],
      "name": "JiaoJiao Wan"
    },
    {
      "affs": [
        0
      ],
      "name": "Xiaoliang Liu"
    },
    {
      "affs": [
        1
      ],
      "name": "Xiaoliang Liu"
    },
    {
      "affs": [
        0
      ],
      "name": "Fan Hu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/03ftn7rvyb96b.bib",
  "cited_by": 0,
  "doi": "10.3389/fmed.2026.1925509",
  "fulltext_url": "https://www.frontiersin.org/articles/10.3389/fmed.2026.1925509/full",
  "id": "03ftn7rvyb96b",
  "issns": [
    "2296-858X"
  ],
  "landing_url": "https://doi.org/10.3389/fmed.2026.1925509",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R5-920"
    ],
    [
      "openalex",
      "2746|Vascular Malformations and Hemangiomas"
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  "openalex": "W7223306096",
  "pdf_url": "https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1925509/pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Frontiers Media S.A.",
  "ris": "https://research.draconitic.com/paper/03ftn7rvyb96b.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:12Z",
      "native_id": "88aa112fc34442a8b611d9fd27343d9e",
      "source": "doaj",
      "url": "https://doi.org/10.3389/fmed.2026.1925509"
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Vascular Malformations and Hemangiomas",
      "subfield": "surgery"
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  ],
  "title": "Case Report: Fetal giant congenital hemangioma with arteriovenous malformation: to be or not to be",
  "title_text": "Case Report: Fetal giant congenital hemangioma with arteriovenous malformation: to be or not to be",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:12Z",
  "url": "https://research.draconitic.com/paper/03ftn7rvyb96b",
  "venue": "Frontiers in Medicine",
  "versions": []
}