{
  "abstract": "A kaolin-derived Cu(ii)-doped zeolite (Cu-Z1) was synthesized through metakaolin activation, alkaline crystallization, and subsequent Cu2+ ion exchange, and immobilized on nickel foam (Cu-Z1/NiF) for electrochemical determination of paracetamol. The synthesized materials were characterized using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM/EDS), X-ray photoelectron spectroscopy (XPS), and thermogravimetric/differential thermogravimetric analysis (TGA/DTGA). The characterization results confirmed preservation of a ZSM-5-type aluminosilicate framework following Cu(ii) incorporation, with accompanying changes in crystallinity, morphology, and surface chemical environment. Electrochemical measurements demonstrated enhanced paracetamol oxidation at Cu-Z1/NiF compared with bare nickel foam and undoped Z1/NiF, giving an anodic peak current of 75.69 µA, a midpoint potential of 355 mV, and reduced charge-transfer resistance. Under optimized conditions, differential pulse voltammetry (DPV) showed a linear response over 5-100 µM paracetamol, with a detection limit of 0.3926 µM, sensitivity of 2.0456 µA µM-1 cm-2, and R2 = 0.9971. The sensor exhibited good selectivity toward paracetamol in the presence of dopamine, uric acid, and glucose, with repeatability below 0.8% RSD. It retained 95.8% of its initial response after 20 days. Analysis of commercial paracetamol tablets produced recoveries of 95.91-99.29%, demonstrating the applicability of the Cu-Z1/NiF sensor for pharmaceutical paracetamol determination.",
  "abstract_shown": true,
  "affiliations": [
    "Institute for Catalysis and Energy Solutions, College of Science, Engineering and Technology (CSET), University of South Africa (UNISA) Florida 1709 Johannesburg South Africa chemeeb@unisa.ac.za maboywk@unisa.ac.za makgwpr@unisa.ac.za adekuas@unisa.ac.za.",
    "Department of Chemistry, College of Natural and Computational Sciences, Dilla University Dilla Ethiopia cberaso22@gmail.com.",
    "Department of Chemical, Metallurgical and Materials Engineering, Tshwane University of Technology Pretoria South Africa MhikeW@tut.ac.za MavhunguL@tut.ac.za."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Endazenaw Bizuneh Chemere",
      "orcid": "0000-0003-1984-912X"
    },
    {
      "affs": [
        1
      ],
      "name": "Chernet Beraso Jigso"
    },
    {
      "affs": [
        2
      ],
      "name": "Washington Mhike",
      "orcid": "0000-0003-4670-1171"
    },
    {
      "affs": [
        2
      ],
      "name": "Mapula Lucey Mavhungu"
    },
    {
      "affs": [
        0
      ],
      "name": "Winny Kgabo Maboya"
    },
    {
      "affs": [
        0
      ],
      "name": "Makgwane Peter Ramashadi"
    },
    {
      "affs": [
        0
      ],
      "name": "Abolanle Saheed Adekunle"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/04snd00q7yaab.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra09658a",
  "fulltext_url": "https://europepmc.org/articles/PMC13715543",
  "id": "04snd00q7yaab",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/MED/42953746",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "2208|Electrochemical sensors and biosensors"
    ]
  ],
  "openalex": "W7224097786",
  "pdf_url": "https://europepmc.org/articles/PMC13715543?pdf=render",
  "pmcid": "PMC13715543",
  "pmid": "42953746",
  "published": "2026-10-28",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/04snd00q7yaab.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:40Z",
      "native_id": "MED:42953746",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42953746"
    },
    {
      "first_seen": "2026-11-01T12:22:49Z",
      "native_id": "PMC13715543",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra09658a"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "heading:Chemistry",
      "subfield": "general"
    }
  ],
  "title": "Kaolin-derived Cu(ii)-doped zeolite supported on nickel foam for electrochemical paracetamol detection.",
  "title_text": "Kaolin-derived Cu(ii)-doped zeolite supported on nickel foam for electrochemical paracetamol detection.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:22:49Z",
  "url": "https://research.draconitic.com/paper/04snd00q7yaab",
  "venue": "RSC advances",
  "versions": []
}