{
  "abstract": "The leading cause of dementia is Alzheimer’s disease (AD). AD disproportionately affects women, a difference that cannot be explained solely by longer life expectancy but rather reflects sex-dependent biological mechanisms. In recent years, sleep disturbances have emerged as a potential modifiable risk factor for AD, as they appear early in the disease course – often preceding cognitive symptoms – and are associated with the accumulation of amyloid and tau pathology. This narrative review synthesizes evidence from human studies examining the influence of biological sex on the relationship between sleep and AD, with a particular focus on obstructive sleep apnea, insomnia, alterations in sleep architecture and microstructure, and circadian rhythm disturbances. A growing body of literature suggests that women may be more vulnerable to the neurocognitive consequences of sleep disturbances, particularly around the menopausal transition, a period characterized by profound hormonal changes that may interact with neurodegenerative processes. Despite this emerging evidence, studies explicitly integrating biological sex, hormonal status, and their interactions with sleep remain very scarce, with some findings showing heterogeneity. This review highlights the need for future research incorporating such data, using stratified and longitudinal designs, to improve our understanding of the mechanisms linking sleep and AD, and to optimize personalized prevention and management strategies for AD.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Géraldine Rauchs"
    },
    {
      "name": "Laura Stankeviciute"
    },
    {
      "name": "Maéva Boulin"
    },
    {
      "name": "Blandine Montagne"
    },
    {
      "name": "Claire André"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/08a4awfz150n0.bib",
  "cited_by": 0,
  "doi": "10.1016/j.msom.2026.06.004",
  "fulltext_url": null,
  "id": "08a4awfz150n0",
  "issns": [
    "1769-4493"
  ],
  "landing_url": "https://hal.science/hal-05733034v1",
  "language": "fr",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.scco"
    ],
    [
      "hal",
      "0.sdv"
    ],
    [
      "openalex",
      "2738|Dementia and Cognitive Impairment Research"
    ]
  ],
  "openalex": "W7172299958",
  "pdf_url": "https://hal.science/hal-05733034/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-31",
  "publisher": "Elsevier Masson",
  "ris": "https://research.draconitic.com/paper/08a4awfz150n0.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:21Z",
      "native_id": "hal-05733034",
      "source": "hal",
      "url": "https://hal.science/hal-05733034v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2738|Dementia and Cognitive Impairment Research",
      "subfield": "psychiatry"
    }
  ],
  "title": "Liens entre sommeil et maladie d’Alzheimer : impact du sexe féminin",
  "title_text": "Liens entre sommeil et maladie d’Alzheimer : impact du sexe féminin",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:21Z",
  "url": "https://research.draconitic.com/paper/08a4awfz150n0",
  "venue": "Médecine du sommeil",
  "versions": []
}