{
  "abstract": "Iris stromal cysts are rare, progressive ocular lesions that can cause visual impairment and amblyopia due to visual axis obstruction, corneal endothelial damage, uveitis, and secondary angle-closure glaucoma. Management is challenging due to recurrence, and surgical resection carries severe risks such as epithelial downgrowth, glaucoma, blindness, and potential loss of the eye. Absolute alcohol-induced sclerosis is a less invasive alternative; however, the literature on technique modifications remains limited. This case report describes the successful management of a primary iris stromal cyst with secondary ocular hypertension in a 9-year-old Filipino male using a modified three-port approach for absolute alcohol-induced sclerosis. The patient presented with a 4-month history of intermittent redness and pain in the left eye and was found to have elevated intraocular pressure (IOP) due to an iris stromal cyst. A modified three-port setup was prepared using a 30-gauge needle connected to a 3-way stopcock, a 3-mL syringe for aspiration, and an extension tube connected to a syringe containing absolute alcohol mixed with trypan blue dye. Although a 3-mL syringe was used for alcohol infusion, a 1-mL syringe may provide finer control. Postoperatively, transient corneal edema, mild anterior chamber inflammation, and steroid-induced intraocular pressure elevation were observed but resolved with medical management. At 18 months post-surgery, the patient remained asymptomatic, with a best-corrected visual acuity of 20/20, well-controlled IOP without medication, and no cyst recurrence. This case illustrates the effectiveness of a modified three-port approach in treating iris stromal cysts while preventing complications such as visual axis obstruction, glaucoma, and the need for more invasive surgery. This technique presents a practical and accessible option, especially in resource-limited settings. The paper also emphasizes the importance of meticulous technique and awareness of alcohol leakage, with key precautions outlined for safe application.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.",
    "Eye Institute, St. Luke's Medical Center, Quezon City, Philippines."
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Bobbie Marie M Santos"
    },
    {
      "affs": [
        0
      ],
      "name": "Jayvee S Rivera"
    },
    {
      "affs": [
        0
      ],
      "name": "George Michael N Sosuan"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Reginald Robert G Tan"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ruben Lim Bon Siong"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/08kfnp4jgbd2e.bib",
  "cited_by": 0,
  "doi": "10.47895/amp.v60i17.13492",
  "fulltext_url": "https://europepmc.org/articles/PMC13713870",
  "id": "08kfnp4jgbd2e",
  "issns": [
    "0001-6071",
    "2094-9278"
  ],
  "landing_url": "https://europepmc.org/article/MED/42952907",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2731|Intraocular Surgery and Lenses"
    ]
  ],
  "openalex": "W7213547726",
  "pdf_url": "https://europepmc.org/articles/PMC13713870?pdf=render",
  "pmcid": "PMC13713870",
  "pmid": "42952907",
  "published": "2026-09-15",
  "publisher": "University of the Philippines Manila",
  "ris": "https://research.draconitic.com/paper/08kfnp4jgbd2e.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T00:20:41Z",
      "native_id": "MED:42952907",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42952907"
    },
    {
      "first_seen": "2026-11-01T12:21:28Z",
      "native_id": "PMC13713870",
      "source": "pmc",
      "url": "https://doi.org/10.47895/amp.v60i17.13492"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Intraocular Surgery and Lenses",
      "subfield": "general"
    }
  ],
  "title": "Modified Three-port Approach for Absolute Alcohol-induced Sclerosis of Iris Stromal Cyst: A Case Report.",
  "title_text": "Modified Three-port Approach for Absolute Alcohol-induced Sclerosis of Iris Stromal Cyst: A Case Report.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:21:28Z",
  "url": "https://research.draconitic.com/paper/08kfnp4jgbd2e",
  "venue": "Acta medica Philippina",
  "versions": []
}