{
  "abstract": "Nocardia spp. and Mycobacterium spp. are known etiological agents of granulomatous pulmonary infections in humans and animals; however, co-infections involving these pathogens have not previously been reported in veterinary medicine. This paper describes the first documented case of co-infection with Mycobacterium bovis and Nocardia spp. in a captive roan antelope (Hippotragus equinus). The animal was a 9-year-old female roan antelope from a safari park in northern Italy that died suddenly with a one-month history of weight loss. Post-mortem examination revealed severe, diffuse, chronic granulomatous pneumonia associated with fibrino-granulomatous pleuritis and granulomatous pericarditis. Histologically, multifocal to coalescing necrotizing granulomas were observed, with intralesional acid-fast bacteria. Microbiological culture and biomolecular analyses allowed the identification of M. bovis and Nocardia spp. in lung tissue samples. The Nocardia genome sequence was 98.5% similar to N. tengchongensis, a recently discovered species. The findings emphasize the importance of comprehensive diagnostic approaches in animal granulomatous lung disease. Mixed infections in captive wildlife represent a One Health concern, as the potential for zoonotic adaptation and transmission to humans cannot be excluded. Therefore, pathogen surveillance is of particular importance within zoological collections.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 9,
  "authors": [
    {
      "name": "Luca Botta"
    },
    {
      "name": "Matteo Cuccato"
    },
    {
      "name": "Neva Cormio"
    },
    {
      "name": "Veronica Crocchianti"
    },
    {
      "name": "Maria Goria"
    },
    {
      "name": "Emanuelle Bergeron"
    },
    {
      "name": "Delphine Mouniée"
    },
    {
      "name": "Veronica Rodriguez Nava"
    },
    {
      "name": "Frine Eleonora Scaglione"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0bqrnszjn8e9m.bib",
  "cited_by": 0,
  "doi": "10.3390/ani16111721",
  "fulltext_url": null,
  "id": "0bqrnszjn8e9m",
  "issns": [
    "2076-2615"
  ],
  "landing_url": "https://hal.inrae.fr/hal-05845680v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.sdv"
    ],
    [
      "hal",
      "1.sdv.ba"
    ],
    [
      "hal",
      "2.sdv.ba.zv"
    ],
    [
      "openalex",
      "2726|Actinomycetales infections and treatment"
    ]
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  "openalex": "W7163585930",
  "pdf_url": "https://hal.inrae.fr/hal-05845680/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-06-04",
  "publisher": "MDPI",
  "ris": "https://research.draconitic.com/paper/0bqrnszjn8e9m.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T12:20:56Z",
      "native_id": "hal-05845680",
      "source": "hal",
      "url": "https://hal.inrae.fr/hal-05845680v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "hal:1.sdv.ba",
      "subfield": "zoology-behaviour"
    }
  ],
  "title": "First Report of Mycobacterium bovis and Nocardia spp. Co-Infection in a Roan Antelope",
  "title_text": "First Report of Mycobacterium bovis and Nocardia spp. Co-Infection in a Roan Antelope",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T12:20:45Z",
  "url": "https://research.draconitic.com/paper/0bqrnszjn8e9m",
  "venue": "Animals",
  "versions": []
}