{
  "abstract": "We report a silver‐catalyzed hydrogen isotope exchange reaction that enables direct deuteration of quinones and related scaffolds, using readily available D 2 O as an isotopic source. The homogeneous Ag 2 SO 4 system provides high isotopic enrichment, up to 99%, with excellent regioselectivity across diverse frameworks, including substituted para ‐naphthoquinones, anthraquinones, coumarins, quinolinones, and chromones. We also developed a heterogeneous version of the same reaction by supporting silver nanoparticles on carbon nanotubes. The nanohybrid catalyst maintains high performance and allows for easy removal of the catalyst from the final product through filtration. The dual homogeneous/heterogeneous approaches pioneer quinone hydrogen isotope exchange, providing practical and straightforward access to isotopologues.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "name": "Joyce de Oliveira"
    },
    {
      "name": "Mateus Nunes"
    },
    {
      "name": "Frédéric Miserque"
    },
    {
      "name": "Valérie Geertsen"
    },
    {
      "name": "Guilherme Jardim"
    },
    {
      "name": "Eric Doris"
    },
    {
      "name": "Eufrânio Júnior"
    },
    {
      "name": "Edmond Gravel"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0cqw5mk9gk02x.bib",
  "cited_by": 0,
  "doi": "10.1002/chem.71584",
  "fulltext_url": null,
  "id": "0cqw5mk9gk02x",
  "issns": [
    "0947-6539",
    "1521-3765"
  ],
  "landing_url": "https://hal.science/hal-05742318v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "openalex",
      "3003|Chemical Reactions and Isotopes"
    ]
  ],
  "openalex": "W7211973864",
  "pdf_url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/chem.71584",
  "pmcid": null,
  "pmid": "42708195",
  "published": "2026-09-08",
  "publisher": "Wiley-VCH Verlag",
  "ris": "https://research.draconitic.com/paper/0cqw5mk9gk02x.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "hal-05742318",
      "source": "hal",
      "url": "https://hal.science/hal-05742318v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:3003|Chemical Reactions and Isotopes",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Silver‐Mediated Deuterium Labelling of Quinones and Related Compounds by Hydrogen Isotope Exchange With D 2 O",
  "title_text": "Silver‐Mediated Deuterium Labelling of Quinones and Related Compounds by Hydrogen Isotope Exchange With D 2 O",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/0cqw5mk9gk02x",
  "venue": "Chemistry - A European Journal",
  "versions": []
}