{
  "abstract": "Aplastic anemia (AA) is an immune-mediated bone marrow failure syndrome. We report a case of severe AA that developed shortly after thymectomy for thymoma. The patient demonstrated monoclonal T-cell receptor β-chain rearrangement and skewed B-cell light-chain expression without evidence of hematologic malignancy. Triple immunosuppressive therapy with horse anti-thymocyte globulin, cyclosporine, and eltrombopag induced rapid hematologic recovery and sustained treatment-free remission. This case expands the clinical spectrum of thymoma-associated aplastic anemia and highlights the importance of recognizing severe AA as a potential complication after thymectomy.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Yusuke Yamaga"
    },
    {
      "name": "Shoichiro Okazaki"
    },
    {
      "name": "Takahiro Nishiyama"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0ef8jd64qpadr.bib",
  "cited_by": 0,
  "doi": "10.2169/internalmedicine.7913-26",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7913-26/_article",
  "id": "0ef8jd64qpadr",
  "issns": [
    "1349-7235",
    "0918-2918"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7913-26/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/general"
    ],
    [
      "openalex",
      "2728|Myasthenia Gravis and Thymoma"
    ]
  ],
  "openalex": "W7214662284",
  "pdf_url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7913-26/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-29",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0ef8jd64qpadr.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:31Z",
      "native_id": "10.2169/internalmedicine.7913-26",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_7913-26/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Myasthenia Gravis and Thymoma",
      "subfield": "neurology"
    }
  ],
  "title": "Severe Aplastic Anemia Following Thymectomy for Thymoma: A Case Suggesting Perturbation of the Adaptive Immune Repertoire",
  "title_text": "Severe Aplastic Anemia Following Thymectomy for Thymoma: A Case Suggesting Perturbation of the Adaptive Immune Repertoire",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:31Z",
  "url": "https://research.draconitic.com/paper/0ef8jd64qpadr",
  "venue": "Internal Medicine",
  "versions": []
}