{
  "abstract": "Summary points:\n\nTraditional antenatal care consists of an accelerating frequency of visits with advancing gestational age, as the bulk of pregnancy complications occur in late pregnancy.\n\nThe ‘inverted pyramid of care’ concept describes a focus on structured risk assessment in early pregnancy, to facilitate prevention and enhanced surveillance of those at increased risk of maternal, intrinsic fetal, and uteroplacental problems.\n\nSince publication of this concept in 2011, it has become clear that early pregnancy screening may be contingent, with a sub-population identified for re-screening in mid- or late pregnancy.\n\nMaternal conditions (such as pre-eclampsia), intrinsic fetal conditions (such as chromosomal abnormalities) and uteroplacental problems (such as placenta accreta spectrum) can now be predicted or identified at earlier stages.\n\nThis Policy Forum advocates for building risk-stratified care pathways around early prediction, prevention, and personalised surveillance. We provide updated guidance for ‘inverted’ antenatal care, including optimal screening timepoints and the most accurate methods of screening.\n\nWe also highlight recent advances in diagnostics and treatment that we anticipate will further improve antenatal care in the future, including development and integration of artificial intelligence-assisted technologies.\n\nIn this Policy Forum, Laura Magee and colleagues provide updated guidance for ‘inverted’ antenatal care, including optimal screening timepoints and the most accurate methods of screening. They also highlight recent advances in diagnostics and treatment, including development and integration of artificial intelligence-assisted technologies.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Women and Children’s Health, School of Life Course and Population Sciences, Faculty of Life Sciences & Medicine, King’s College London, London, United Kingdom",
    "Fetal Medicine Research Institute, King’s College Hospital, London, United Kingdom"
  ],
  "article_type": "Policy Forum",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Laura A. Magee"
    },
    {
      "affs": [
        1
      ],
      "name": "Peter von Dadelszen"
    },
    {
      "name": "Kypros H. Nicolaides"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0enhntbw40f4w.bib",
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  "doi": "10.1371/journal.pmed.1005255",
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  "id": "0enhntbw40f4w",
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  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
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      "/Medicine and health sciences/Women's health/Maternal health/Pregnancy/Pregnancy complications/Preeclampsia"
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      "/Medicine and health sciences/Women's health/Maternal health/Pregnancy/Pregnancy complications/Preterm birth"
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      "/Medicine and health sciences/Women's health/Obstetrics and gynecology/Birth"
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      "/Medicine and health sciences/Women's health/Obstetrics and gynecology/Pregnancy"
    ],
    [
      "plos",
      "/Medicine and health sciences/Women's health/Obstetrics and gynecology/Pregnancy/Pregnancy complications/Preeclampsia"
    ],
    [
      "plos",
      "/Medicine and health sciences/Women's health/Obstetrics and gynecology/Pregnancy/Pregnancy complications/Preterm birth"
    ],
    [
      "plos",
      "/Medicine and health sciences/Women's health/Obstetrics and gynecology/Stillbirths"
    ],
    [
      "plos",
      "/Research and analysis methods/Imaging techniques/Diagnostic radiology/Ultrasound imaging"
    ]
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  "pdf_url": "https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1005255&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-28",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/0enhntbw40f4w.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:37Z",
      "native_id": "10.1371/journal.pmed.1005255",
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  "subjects": [
    {
      "field": "medicine",
      "origin": "plos:women's health",
      "subfield": "reproductive-child"
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  ],
  "title": "The inverted pyramid of care in modern-day obstetrics",
  "title_text": "The inverted pyramid of care in modern-day obstetrics",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:37Z",
  "url": "https://research.draconitic.com/paper/0enhntbw40f4w",
  "venue": "PLOS Medicine",
  "versions": []
}