{
  "abstract": "To mitigate human exposure to air pollutants amid the increasing chemicalization of daily life, simple and rapid monitoring methods are required. As individuals spend a significant portion of their time indoors, indoor air quality has become a critical factor affecting human health and is influenced by a wide range of indoor and outdoor pollution sources. The sorption and desorption of indoor air pollutants on solid surfaces (the so-called sink effect) can gradually increase pollutant concentrations and lead to changes in indoor air quality. In particular, third-hand smoke (THS), a persistent form of indoor pollution, poses potential health risks through inhalation, dermal contact, and ingestion. Air sampling and analysis can be tedious and costly. Here, we present a very simple method that unifies passive sampling of THS onto paper and subsequent analysis by paper spray ionization (PSI) mass spectrometry (MS). Mass spectrometric results revealed the presence of nicotine, a major constituent of tobacco smoke, in THS samples collected using a custom-built passive sampler, which was further confirmed by MS/MS analysis. The applicability of this approach was further extended to a forensic context by detecting nicotine on book pages, which were previously exposed to cigarette smoke, using filter papers as sampling media. Overall, passive air sampling onto paper─combined with PSI-MS─provides a simple, cost-effective, and time-efficient way for indoor air quality monitoring and forensic analysis.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu300044, Taiwan."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Bo-Cheng Ke"
    },
    {
      "affs": [
        0
      ],
      "name": "Noor Hidayat Abu Bakar"
    },
    {
      "affs": [
        0
      ],
      "name": "Pawel L Urban",
      "orcid": "0000-0003-3471-045X"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0fpcgmrqqcjph.bib",
  "cited_by": 0,
  "doi": "10.1021/jasms.6c00271",
  "fulltext_url": "https://europepmc.org/articles/PMC13651622",
  "id": "0fpcgmrqqcjph",
  "issns": [
    "1044-0305",
    "1879-1123"
  ],
  "landing_url": "https://europepmc.org/article/MED/42916758",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1607|Mass Spectrometry Techniques and Applications"
    ]
  ],
  "openalex": "W7211943206",
  "pdf_url": "https://europepmc.org/articles/PMC13651622?pdf=render",
  "pmcid": "PMC13651622",
  "pmid": "42916758",
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0fpcgmrqqcjph.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:36Z",
      "native_id": "MED:42916758",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42916758"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1607|Mass Spectrometry Techniques and Applications",
      "subfield": "physical"
    }
  ],
  "title": "Unifying Passive Air Sampling with Paper Spray Ionization Mass Spectrometry for the Detection of Third-Hand Cigarette Smoke.",
  "title_text": "Unifying Passive Air Sampling with Paper Spray Ionization Mass Spectrometry for the Detection of Third-Hand Cigarette Smoke.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:36Z",
  "url": "https://research.draconitic.com/paper/0fpcgmrqqcjph",
  "venue": "Journal of the American Society for Mass Spectrometry",
  "versions": []
}