{
  "abstract": "The design of functional coordination polymers with enzyme-mimicking activity has attracted considerable interest for the development of sensitive, cost-effective sensing platforms. Herein, we report the uric acid sensing properties of a three-dimensional Cu(I)-based coordination polymer constructed from a thioether-functionalized polyhedral oligomeric silsesquioxane (POSS) ligand. The POSS-Cu Coordination polymer (PCCP) exhibits efficient peroxidase-like activity, catalyzing the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H 2 O 2 to produce a blue product (oxTMB), showing a strong absorption band at 652 nm. Steady-state kinetic studies reveal typical Michaelis-Menten behaviour with low Michaelis constants (K m ) values of 0.166 mM H 2 O 2 and 0.0457 mM for TMB, demonstrating a high affinity toward both substrates. The developed sensing strategy utilizes the reducing ability of UA to convert oxTMB into its colorless form, resulting in a concentration-dependent decrease in absorbance that enables quantitative determination of UA. Under optimized conditions, the colorimetric assay exhibits a linear response with a detection limit of 0.25 μM with excellent repeatability and high selectivity. Moreover, the catalyst retains its catalytic performance over repeated cycles, demonstrating excellent operational stability and making it a promising platform for sensitive, reliable, and cost-effective uric acid analysis.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Arosmit Mohanty"
    },
    {
      "name": "Anrudh Mishra"
    },
    {
      "name": "Lydie Viau"
    },
    {
      "name": "Michael Knorr"
    },
    {
      "name": "Abhinav Raghuvanshi"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0gmc4bg31m9bj.bib",
  "cited_by": 0,
  "doi": "10.1016/j.microc.2026.120062",
  "fulltext_url": null,
  "id": "0gmc4bg31m9bj",
  "issns": [
    "0026-265X",
    "1095-9149"
  ],
  "landing_url": "https://hal.science/hal-05847062v1",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "openalex",
      "2505|Advanced Nanomaterials in Catalysis"
    ]
  ],
  "openalex": "W7223120839",
  "pdf_url": "https://hal.science/hal-05847062/document",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-21",
  "publisher": "Elsevier",
  "ris": "https://research.draconitic.com/paper/0gmc4bg31m9bj.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T12:20:17Z",
      "native_id": "hal-05847062",
      "source": "hal",
      "url": "https://hal.science/hal-05847062v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2505|Advanced Nanomaterials in Catalysis",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Peroxidase-like activity of a POSS-based Cu(I) coordination polymer for colorimetric uric acid detection",
  "title_text": "Peroxidase-like activity of a POSS-based Cu(I) coordination polymer for colorimetric uric acid detection",
  "type": "peer-reviewed",
  "updated_at": "2026-11-03T12:20:17Z",
  "url": "https://research.draconitic.com/paper/0gmc4bg31m9bj",
  "venue": "Microchemical Journal",
  "versions": []
}