{
  "abstract": "amide coupling to yield multifunctional constructs. The colloidal properties of the resulting NPs were assessed by dynamic light scattering (DLS), while drug and aptamer loadings were quantified by the fluorescence emission of the coumarinyl scaffold and Cy5-labelled aptamer, respectively. When SPAAC conjugation was implemented, higher aptamer and drug contents were observed, pointing toward the impact of surface chemistries on the availability of surface reactive handles for downstream functionalization. Overall, this work establishes peptide-coated LNO NPs as a versatile scaffold for the orthogonal anchoring of aptamer and caged therapeutic cargos, paving the way toward decoupled nonlinear optical imaging and light-triggered drug delivery.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "Alessandra Spada"
    },
    {
      "name": "Adrian Gheata"
    },
    {
      "name": "Ameni Dhouib"
    },
    {
      "name": "Yannick Mugnier"
    },
    {
      "name": "Sandrine Gerber-Lemaire"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0h5fmrq7tz2rb.bib",
  "cited_by": 0,
  "doi": "10.1039/d6lf00132g",
  "fulltext_url": null,
  "id": "0h5fmrq7tz2rb",
  "issns": [
    "2755-3701"
  ],
  "landing_url": "https://hal.science/hal-05769946v1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "hal",
      "0.chim"
    ],
    [
      "openalex",
      "2502|Nanoparticle-Based Drug Delivery"
    ]
  ],
  "openalex": "W7202351495",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-13",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/0h5fmrq7tz2rb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:43Z",
      "native_id": "hal-05769946",
      "source": "hal",
      "url": "https://hal.science/hal-05769946v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2502|Nanoparticle-Based Drug Delivery",
      "subfield": "materials-polymers"
    }
  ],
  "title": "Orthogonal functionalization of lithium niobate nanoparticles with targeting aptamers and caged chemotherapeutics",
  "title_text": "Orthogonal functionalization of lithium niobate nanoparticles with targeting aptamers and caged chemotherapeutics",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:43Z",
  "url": "https://research.draconitic.com/paper/0h5fmrq7tz2rb",
  "venue": "RSC Applied Interfaces",
  "versions": []
}