{
  "abstract": "Purpose\n\nOutcome after aneurysmal subarachnoid hemorrhage (aSAH) is often devastating with life time issues also for independent survivors. We aimed to identify health related quality of life (HRQoL) issues in this favorable functional outcome group compared to a sex and age matched general population.Methods\n\nWe have analyzed data from 634 Swedish aSAH patients from a national prospective study ranging between 2014 and 2018. One year after ictus, functional outcome was analyzed using Glasgow Outcome Scale Extended (GOSE) and HRQoL assessed by Euro-quality of life-5 dimensions-3 levels (EQ-5D-3L). Favorable GOSE (5-8) were found in 471 patients. Age- and sex-matched populations were created by published data from a cross-sectional cohort of 32,597 people living in Stockholm County in 2006. Odds ratios (ORs) for rating a specific EQ-5D-3L level were calculated for each domain. Significance was set at α = 0.001.Results\n\nPatients reported less mobility problems than the matched general population (9.6% vs 14.7%; OR 0.62 p = 0.002). However, with usual activities significantly more difficulties with moderate, (24.0% vs 10.9%; OR 2.58, p < .001) and any problems (27.0% vs 12.5%; OR 2.58, p < .001) were reported. More issues with extreme anxiety/depression were also reported ((5.3% vs 2.8%; OR 1.94; p = 0.002). Unfavorable GOSE patients were doing worse than the matched population in all levels and dimensions measured (Online Resource 1, 2, 3 and 4).Conclusion\n\nAlthough patients with favorable functional outcome report good or better mobility compared to their age and sex matched general population, they have significantly more issues with usual activities a year after aSAH more extreme issues with anxiety/depression were also reported To our knowledge, this is the first time EQ-5D-3L data is compared in a national group of aSAH patients with favorable functional outcome to a sex and age matched general population.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Clinical Sciences - Neurosciences, Umeå University, 901 87, Umeå, Sweden. helena.aineskog@umu.se.",
    "Department of Clinical Sciences - Neurosurgery, Lund University, Lund, Sweden.",
    "Institute of Neuroscience and Physiology, Department of Clinical Neuroscience, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.",
    "Department of Medical Sciences, Section of Neurosurgery, Uppsala University, Uppsala, Sweden.",
    "Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.",
    "Department of Clinical Sciences, Linköping University, Linköping, Sweden.",
    "Department of Clinical Sciences - Neurosciences, Umeå University, 901 87, Umeå, Sweden."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Helena Aineskog",
      "orcid": "0000-0003-3354-4146"
    },
    {
      "affs": [
        1
      ],
      "name": "Bryndís Baldvinsdóttir"
    },
    {
      "affs": [
        1
      ],
      "name": "Ola G Nilsson"
    },
    {
      "affs": [
        2
      ],
      "name": "Asgeir S Jakola"
    },
    {
      "affs": [
        1
      ],
      "name": "Erik Kronvall"
    },
    {
      "affs": [
        3
      ],
      "name": "Elisabeth Ronne Engström"
    },
    {
      "affs": [
        2
      ],
      "name": "Paula Klurfan"
    },
    {
      "affs": [
        4
      ],
      "name": "Peter Alpkvist"
    },
    {
      "affs": [
        4
      ],
      "name": "Mikael Svensson"
    },
    {
      "affs": [
        5
      ],
      "name": "Jan Hillman"
    },
    {
      "affs": [
        6
      ],
      "name": "Peter Lindvall"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0hczf2vn87qsy.bib",
  "cited_by": 0,
  "doi": "10.1007/s00701-026-07059-z",
  "fulltext_url": "https://europepmc.org/articles/PMC13676643",
  "id": "0hczf2vn87qsy",
  "issns": [
    "0001-6268",
    "0942-0940"
  ],
  "landing_url": "https://europepmc.org/article/MED/42891758",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2728|Intracranial Aneurysms: Treatment and Complications"
    ]
  ],
  "openalex": "W7222558904",
  "pdf_url": "https://europepmc.org/articles/PMC13676643?pdf=render",
  "pmcid": "PMC13676643",
  "pmid": "42891758",
  "published": "2026-10-16",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0hczf2vn87qsy.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:46Z",
      "native_id": "MED:42891758",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42891758"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Intracranial Aneurysms: Treatment and Complications",
      "subfield": "neurology"
    }
  ],
  "title": "Targeting health-related quality of life issues not found with functional outcome measures a year after aneurysm subarachnoid hemorrhage in a Swedish national cohort.",
  "title_text": "Targeting health-related quality of life issues not found with functional outcome measures a year after aneurysm subarachnoid hemorrhage in a Swedish national cohort.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:46Z",
  "url": "https://research.draconitic.com/paper/0hczf2vn87qsy",
  "venue": "Acta neurochirurgica",
  "versions": []
}