{
  "abstract": "Objective We performed a retrospective cohort analysis to assess the association between mean airway pressure (Pmean) during mechanical ventilation and 90-day mortality in patients with ventilator-associated pneumonia (VAP). Results Of the 2,911 VAP cases retrieved from MIMIC-IV, 693 patients (23.8%) had died within 90 days. Non-survivors showed a significantly higher average Pmean than survivors (median [IQR]:10.80 [8.85, 13.89] vs. 9.89 [8.28, 12.04]; P < 0.001). The area under the receiver operating characteristic (ROC) curve (AUC) for average Pmean was 0.591. When patients were divided by median Pmean (10.06 cmH₂O), those with higher values had worse 90-day survival (log-rank P < 0.001). Conclusions Higher average Pmean was associated with increased 90-day mortality in VAP. These univariable results suggest an association, but validation with multivariable and prospective studies is needed.",
  "abstract_shown": true,
  "affiliations": [
    "Shenzhen Luohu Hospital Group",
    "Shenzhen Hospital, Shanghai University of Traditional Chinese Medicine"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hai Huang"
    },
    {
      "affs": [
        0
      ],
      "name": "Aihua Wang"
    },
    {
      "affs": [
        1
      ],
      "name": "Wenzhen Wu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0j2dczhv0q1fa.bib",
  "cited_by": 0,
  "doi": "10.1186/s43168-026-00707-z",
  "fulltext_url": "https://doi.org/10.1186/s43168-026-00707-z",
  "id": "0j2dczhv0q1fa",
  "issns": [
    "1687-8426",
    "2314-8551"
  ],
  "landing_url": "https://doi.org/10.1186/s43168-026-00707-z",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC705-779"
    ],
    [
      "lcc",
      "RC86-88.9"
    ],
    [
      "openalex",
      "2706|Nosocomial Infections in ICU"
    ]
  ],
  "openalex": "W7223178841",
  "pdf_url": "https://link.springer.com/content/pdf/10.1186/s43168-026-00707-z.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-25",
  "publisher": "SpringerOpen",
  "ris": "https://research.draconitic.com/paper/0j2dczhv0q1fa.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:50Z",
      "native_id": "f48c2fd93cc64fee9a1aba526b2df4f8",
      "source": "doaj",
      "url": "https://doi.org/10.1186/s43168-026-00707-z"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2706|Nosocomial Infections in ICU",
      "subfield": "general"
    }
  ],
  "title": "Association between mean airway pressure and 90-day mortality in ventilator-associated pneumonia",
  "title_text": "Association between mean airway pressure and 90-day mortality in ventilator-associated pneumonia",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:50Z",
  "url": "https://research.draconitic.com/paper/0j2dczhv0q1fa",
  "venue": "The Egyptian Journal of Bronchology",
  "versions": []
}