{
  "abstract": "A visible-light-driven photocatalytic protocol was developed for the synthesis of diverse quinazoline derivatives using a recyclable CuO/TiO₂ nanocomposite as a heterogeneous catalyst. Characterization by XRD, FT-IR, FE-SEM, and UV-Vis DRS confirmed the successful fabrication of the composite with enhanced visible-light absorption. Under blue-LED irradiation and ambient air, the CuO/TiO₂ catalyst effectively mediated the cascade oxidation of 2-aminobenzyl alcohol to 2-aminobenzaldehyde, followed by condensation with benzaldehydes and an ammonia source to afford a broad scope of quinazolines in good to excellent isolated yields (89-96%). Radical-trapping experiments demonstrated that superoxide radical species (O₂˙⁻) and photogenerated holes (h⁺) play pivotal roles in the catalytic transformation. Furthermore, the catalyst exhibited good operational stability and could be recycled over multiple consecutive cycles without significant loss of catalytic activity.",
  "abstract_shown": true,
  "affiliations": [
    "Department of New Materials, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology P.O. Box 76315-117 Kerman Iran ahassankhani@gmail.com +98 3426226617 +98 3426226611-12.",
    "Department of Chemistry, Faculty of Science, University of Jiroft P.O. Box 8767161167 Jiroft Iran a.akbari@ujiroft.ac.ir +98-344-334-7061 +98-344-334-7065."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Danial Zand Hoseinshahi"
    },
    {
      "affs": [
        0
      ],
      "name": "Asadollah Hassankhani"
    },
    {
      "affs": [
        1
      ],
      "name": "Ali Akbari",
      "orcid": "0000-0002-0891-8620"
    },
    {
      "affs": [
        0
      ],
      "name": "Batoul Lashkari"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0n53k8pr1yw33.bib",
  "cited_by": 0,
  "doi": "10.1039/d6ra09408b",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13725858/?tool=EBI",
  "id": "0n53k8pr1yw33",
  "issns": [
    "2046-2069"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13725858",
  "language": "eng",
  "licence": "CC-BY-NC",
  "licence_label": "CC BY-NC",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Chemistry"
    ],
    [
      "openalex",
      "1605|Quinazolinone synthesis and applications"
    ]
  ],
  "openalex": "W7225075488",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13725858/pdf/?tool=EBI",
  "pmcid": "PMC13725858",
  "pmid": "42974426",
  "published": "2026-11-02",
  "publisher": "Royal Society of Chemistry",
  "ris": "https://research.draconitic.com/paper/0n53k8pr1yw33.ris",
  "sources": [
    {
      "first_seen": "2026-11-03T15:20:51Z",
      "native_id": "PMC:PMC13725858",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13725858"
    },
    {
      "first_seen": "2026-11-04T15:20:47Z",
      "native_id": "MED:42974426",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42974426"
    },
    {
      "first_seen": "2026-11-05T12:22:18Z",
      "native_id": "PMC13725858",
      "source": "pmc",
      "url": "https://doi.org/10.1039/d6ra09408b"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Quinazolinone synthesis and applications",
      "subfield": "organic"
    }
  ],
  "title": "Visible-light-driven synthesis of quinazoline derivatives using a recyclable CuO/TiO2 nanocomposite photocatalyst",
  "title_text": "Visible-light-driven synthesis of quinazoline derivatives using a recyclable CuO/TiO2 nanocomposite photocatalyst",
  "type": "peer-reviewed",
  "updated_at": "2026-11-06T12:21:56Z",
  "url": "https://research.draconitic.com/paper/0n53k8pr1yw33",
  "venue": "RSC advances",
  "versions": []
}