{
  "abstract": "Rural cancer survivors may face structural barriers to symptom management and rehabilitation, yet rural-urban differences in pain and physical function remain understudied. This secondary analysis examined rural-urban differences in pain intensity, pain interference, and physical function among 232 adults receiving care at a National Cancer Institute-designated cancer center in Oklahoma. Rural-urban residence was classified using 2020 Rural-Urban Commuting Area codes based on residential ZIP code. Outcomes were assessed using the Patient-Reported Outcomes Measurement Information System-29. Multivariable linear regression and mixed-effects models examined baseline and longitudinal associations, adjusting for sociodemographic and clinical covariates. Among participants, 92 (39.7%) were rural and 140 (60.3%) were urban. Compared with urban participants, rural participants reported higher baseline pain intensity (4.3 vs 3.2; p = 0.003), higher pain interference (57.3 vs 53.6; p = 0.011), and lower physical function (41.8 vs 44.4; p = 0.034). In longitudinal models, rural residence remained associated with higher pain intensity (β = 0.99; p = 0.006), higher pain interference (β = 3.45; p = 0.018), and lower physical function (β = -2.51; p = 0.048). Findings support targeted pain management, rehabilitation, and virtual care strategies for rural cancer survivors.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "Gaurav Kumar"
    },
    {
      "name": "Motolani E. Ogunsanya"
    },
    {
      "name": "Amy M. Cohn"
    },
    {
      "name": "Deeksha Gupta"
    },
    {
      "name": "Nathalia M. Machado"
    },
    {
      "name": "Brittany L. Hudson"
    },
    {
      "name": "Munjireen Sifat"
    },
    {
      "name": "Christina Henson"
    },
    {
      "name": "Susanna Ulahannan"
    },
    {
      "name": "Darla E. Kendzor"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0nnf5t9z559e8.bib",
  "cited_by": 0,
  "doi": "10.21203/rs.3.rs-10832930/v1",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13742806/",
  "id": "0nnf5t9z559e8",
  "issns": [
    "2693-5015"
  ],
  "landing_url": "https://doi.org/10.21203/rs.3.rs-10832930/v1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Article"
    ],
    [
      "openalex",
      "2730|Cancer survivorship and care"
    ]
  ],
  "openalex": "W7221795676",
  "pdf_url": "https://www.researchsquare.com/article/rs-10832930/latest.pdf",
  "pmcid": "PMC13742806",
  "pmid": "42999492",
  "published": "2026-10-14",
  "publisher": "American Journal Experts",
  "ris": "https://research.draconitic.com/paper/0nnf5t9z559e8.ris",
  "sources": [
    {
      "first_seen": "2026-11-10T12:23:35Z",
      "native_id": "PMC13742806",
      "source": "pmc",
      "url": "https://doi.org/10.21203/rs.3.rs-10832930/v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Cancer survivorship and care",
      "subfield": "oncology"
    }
  ],
  "title": "Rural-urban differences in pain intensity, pain interference, and physical function among cancer survivors",
  "title_text": "Rural-urban differences in pain intensity, pain interference, and physical function among cancer survivors",
  "type": "preprint",
  "updated_at": "2026-11-10T12:23:35Z",
  "url": "https://research.draconitic.com/paper/0nnf5t9z559e8",
  "venue": "Research Square",
  "versions": []
}