{
  "abstract": "The volatile fraction (VF) of the aerial parts of Sphagnum magellanicum Brid. (Sphagnaceae), collected in southern Ecuador (2740 m a.s.l), was obtained for the first time by steam distillation using a Dean–Stark adapted apparatus and characterized by gas chromatography coupled to mass spectrometry (GC-MS) and flame ionization detection (GC-FID). A total of 89 compounds representing 95.28 ± 1.95% of the total VF were identified. The predominant chemical classes were n-alkanes (39.94%), alcohols (17.56%), sesquiterpene hydrocarbons (13.10%), and oxygenated sesquiterpenes (6.48%). Phytol was the major single compound (16.09 ± 0.07%), followed by n-tricosane (9.25 ± 0.82%), n-heneicosane (9.17 ± 0.54%), hexacosane (7.30 ± 0.99%), nonacosane (5.42 ± 0.14%), (Z)-caryophyllene (4.08 ± 0.32%), hexadecanoic acid (3.64 ± 0.25%), and dotriacontane (2.93 ± 0.21%). The VF was evaluated in vitro for acetylcholinesterase (AChE) inhibitory activity using the Ellman colorimetric assay, yielding a moderate inhibitory effect with an IC50 value of 77.0 ± 1.03 µg/mL. These results provide the first phytochemical and pharmacological characterization of S. magellanicum from Ecuador, establishing it as a potential source of bioactive volatile constituents with potential relevance for further pharmacological investigation.",
  "abstract_shown": true,
  "affiliations": [
    "Departamento de Química, Universidad Técnica Particular de Loja, Loja 110107, Ecuador",
    "Carrera de Ingeniería Química, Universidad Técnica Particular de Loja, Loja 110107, Ecuador",
    "Biodiversidad de Ecosistemas Tropicales-BIETROP, Herbario HUTPL, Departamento de Ciencias Biológicas y Agropecuarias, Universidad Técnica Particular de Loja (UTPL), Calle Paris s/n y Praga, Loja 110107, Ecuador"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "James Calva",
      "orcid": "0000-0003-0608-8990"
    },
    {
      "affs": [
        1
      ],
      "name": "Juan Francisco Dávila"
    },
    {
      "affs": [
        0
      ],
      "name": "Eduardo Valarezo",
      "orcid": "0000-0001-9958-5042"
    },
    {
      "affs": [
        2
      ],
      "name": "Ángel Benítez",
      "orcid": "0000-0003-4579-1291"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0qbecnq4r06ma.bib",
  "cited_by": 0,
  "doi": "10.3390/molecules31213797",
  "fulltext_url": null,
  "id": "0qbecnq4r06ma",
  "issns": [
    "1420-3049"
  ],
  "landing_url": "https://www.mdpi.com/1420-3049/31/21/3797",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1110|Phytochemistry and Biological Activities"
    ]
  ],
  "openalex": "W7223177018",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-22",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/0qbecnq4r06ma.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:42Z",
      "native_id": "10.3390/molecules31213797",
      "source": "crossref",
      "url": "https://www.mdpi.com/1420-3049/31/21/3797"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Phytochemistry and Biological Activities",
      "subfield": "plant-biology"
    }
  ],
  "title": "Chemical Composition and Acetylcholinesterase Inhibitory Activity of the Volatile Fraction from the Ecuadorian Moss Sphagnum magellanicum Brid",
  "title_text": "Chemical Composition and Acetylcholinesterase Inhibitory Activity of the Volatile Fraction from the Ecuadorian Moss Sphagnum magellanicum Brid",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:18:42Z",
  "url": "https://research.draconitic.com/paper/0qbecnq4r06ma",
  "venue": "Molecules",
  "versions": []
}