{
  "abstract": "Thymic epithelial tumors (TETs) are rare and diverse cancers with distinctive immune features, limited prospective evidence, and few systemic options. Their association with autoimmunity, especially thymomas, complicates treatment decisions. This review examines molecular profiling and predictive biomarkers in TET and explores new treatment strategies. We highlight priorities for future trials, global registries, and real-world data to expand access to expert, multidisciplinary care, charting a path toward precision-guided, combination-based treatments.",
  "abstract_shown": true,
  "affiliations": [
    "Dana-Farber Cancer Institute, Boston, MA USA",
    "Indiana University School of Medicine, Indianapolis, IN USA",
    "Stanford University, Palo Alto, CA USA",
    "The University of Chicago Medicine, Chicago, IL USA",
    "MD Anderson Cancer Center, Houston, TX USA",
    "University of California, Davis, Davis, CA USA",
    "Gustave Roussy, Villejuif, France",
    "University of California, Los Angeles, Santa Monica, CA USA",
    "Mayo Clinic Rochester, Rochester, MN USA",
    "Mass General Brigham Cancer Institute at MGH Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Boston, MA USA",
    "Georgetown University, Washington, DC USA"
  ],
  "article_type": "review article",
  "arxiv": null,
  "author_total": 16,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Jennifer A. Marks"
    },
    {
      "affs": [
        1
      ],
      "name": "Rohan Maniar"
    },
    {
      "affs": [
        2
      ],
      "name": "Kavitha J. Ramchandran"
    },
    {
      "affs": [
        3
      ],
      "name": "Erica Pietroluongo"
    },
    {
      "affs": [
        4
      ],
      "name": "Mehmet Altan"
    },
    {
      "affs": [
        5
      ],
      "name": "Surbhi Singhal"
    },
    {
      "affs": [
        0,
        6
      ],
      "name": "Mihaela Aldea"
    },
    {
      "affs": [
        7
      ],
      "name": "Jonathan W. Goldman"
    },
    {
      "affs": [
        5
      ],
      "name": "Jonathan W. Reiss"
    },
    {
      "affs": [
        2
      ],
      "name": "Heather Wakelee"
    },
    {
      "affs": [
        1
      ],
      "name": "Patrick J. Loehrer"
    },
    {
      "affs": [
        3
      ],
      "name": "Marina Chiara Garassino"
    },
    {
      "affs": [
        8
      ],
      "name": "Anja C. Roden"
    },
    {
      "affs": [
        6
      ],
      "name": "Jordi Remon"
    },
    {
      "affs": [
        9
      ],
      "name": "Christopher S. Nabel"
    },
    {
      "affs": [
        10
      ],
      "name": "Chul Kim"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0qxbwdn422yc1.bib",
  "cited_by": 0,
  "doi": "10.1038/s41698-026-01574-z",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13740308/",
  "id": "0qxbwdn422yc1",
  "issns": [
    "2397-768X"
  ],
  "landing_url": "https://doi.org/10.1038/s41698-026-01574-z",
  "language": "en",
  "licence": "CC-BY-NC-ND-4.0",
  "licence_label": "CC BY-NC-ND 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Review"
    ],
    [
      "openalex",
      "2728|Myasthenia Gravis and Thymoma"
    ]
  ],
  "openalex": "W7166165020",
  "pdf_url": "https://www.nature.com/articles/s41698-026-01574-z_reference.pdf",
  "pmcid": "PMC13740308",
  "pmid": "42363019",
  "published": "2026-06-26",
  "publisher": "Nature Publishing Group",
  "ris": "https://research.draconitic.com/paper/0qxbwdn422yc1.ris",
  "sources": [
    {
      "first_seen": "2026-11-10T12:21:35Z",
      "native_id": "PMC13740308",
      "source": "pmc",
      "url": "https://doi.org/10.1038/s41698-026-01574-z"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Myasthenia Gravis and Thymoma",
      "subfield": "neurology"
    }
  ],
  "title": "Redefining therapeutic horizons in thymic epithelial tumors: precision, combinations, and emerging biology",
  "title_text": "Redefining therapeutic horizons in thymic epithelial tumors: precision, combinations, and emerging biology",
  "type": "peer-reviewed",
  "updated_at": "2026-11-10T12:21:35Z",
  "url": "https://research.draconitic.com/paper/0qxbwdn422yc1",
  "venue": "NPJ Precision Oncology",
  "versions": []
}