{
  "abstract": "As a pivotal industrial chemical, adipic acid (AA) is synthesizable through the electrocatalytic oxidation of cyclohexanol under ambient conditions, utilizing electrons as a clean oxidant. This approach circumvents the energy-intensive and environmentally detrimental nature of conventional petrochemical processes, thereby offering a sustainable alternative for AA production. However, existing electrocatalysts are often plagued by instability in alkaline media, and their structure-activity relationships remain poorly understood. Here, we report a novel [Ni₃₆] nanocage-based metal-organic framework ([Ni₉]-MOF) synthesized via a bottom-up strategy from discrete [Ni₉]-clusters, exhibiting excellent stability under both strong alkaline (8 M NaOH) and acidic (1 M HCl) conditions. [Ni₉]-MOF demonstrates superior AA production (0.1239 mmol h⁻¹ cm⁻² at 1.61 V), and maintains this high activity over 25 cycles with negligible loss, surpassing all prior high-performance catalysts in durability. Mechanistic studies reveal a three-step oxidation pathway via cyclohexanone, 2-hydroxycyclohexanone and 6-hydroxyadipic acid. Density functional theory calculations indicate the MOF framework enhances the charge density at the active [Ni₉] site, accelerating reaction kinetics. This work not only provides a rational design strategy for constructing highly stable MOFs, but also presents the first MOF-based electrocatalyst for AA synthesis, opening new avenues for sustainable chemical production under mild conditions.",
  "abstract_shown": true,
  "affiliations": [
    "Frontiers Science Center for New Organic Matter, Key Laboratory of Advanced Energy Materials Chemistry (MOE), College of Chemistry, Nankai University, Tianjin 300071, China.",
    "School of Medicine, Nankai University, Tianjin 300071, China.",
    "Ganjiang Innovation Academy, Jiangxi Institute of Rare Earths, Chinese Academy of Sciences, Ganzhou 341000, China."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 12,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Ze-Long Liang"
    },
    {
      "affs": [
        1
      ],
      "name": "Rui Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Zhen-Ting Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Jia-Can Lv"
    },
    {
      "affs": [
        0
      ],
      "name": "Xin-Min Ai"
    },
    {
      "affs": [
        0
      ],
      "name": "Qi Li"
    },
    {
      "affs": [
        0
      ],
      "name": "Ying-Ying Yu"
    },
    {
      "affs": [
        0
      ],
      "name": "Yang-Xi Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Fang-Ting Zhu"
    },
    {
      "affs": [
        0
      ],
      "name": "Qi-Fan Wang"
    },
    {
      "affs": [
        0
      ],
      "name": "Hang Xu"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Bin Zhao"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0rgvv5fbkfyar.bib",
  "cited_by": 0,
  "doi": "10.1093/nsr/nwag427",
  "fulltext_url": "https://europepmc.org/articles/PMC13678815",
  "id": "0rgvv5fbkfyar",
  "issns": [
    "2095-5138",
    "2053-714X"
  ],
  "landing_url": "https://europepmc.org/article/MED/42898770",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2105|Electrocatalysts for Energy Conversion"
    ]
  ],
  "openalex": "W7168047602",
  "pdf_url": "https://europepmc.org/articles/PMC13678815?pdf=render",
  "pmcid": "PMC13678815",
  "pmid": "42898770",
  "published": "2026-07-11",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0rgvv5fbkfyar.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:42Z",
      "native_id": "MED:42898770",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42898770"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2105|Electrocatalysts for Energy Conversion",
      "subfield": "electrochemistry-energy"
    }
  ],
  "title": "Highly recyclable and efficient electrocatalytic synthesis of adipic acid catalyzed by ultra-alkali-resistant [Ni₃₆] nanocages in MOF.",
  "title_text": "Highly recyclable and efficient electrocatalytic synthesis of adipic acid catalyzed by ultra-alkali-resistant [Ni₃₆] nanocages in MOF.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:42Z",
  "url": "https://research.draconitic.com/paper/0rgvv5fbkfyar",
  "venue": "National science review",
  "versions": []
}