{
  "abstract": "According to the most recent guidelines, uncomplicated acute appendicitis could be treated conservatively using broad‐spectrum antibiotics, but if radiological signs of appendix rupture are present, appendectomy should be considered as first‐line treatment. There is limited evidence in literature regarding the non‐operative management of complicated acute appendicitis, particularly in the subset of patients with Crohn's disease. Intestinal and contrast‐enhanced ultrasound appear pivotal to both diagnosing complications and promptly identifying the non‐responding patients. We describe two cases of complicated acute appendicitis, successfully treated with broad‐spectrum antibiotic therapy and tight monitoring with both intestinal and contrast‐enhanced ultrasound, in patients with Crohn's disease.",
  "abstract_shown": true,
  "affiliations": [
    "Gastroenterology Unit, Department of Biomedical and Clinical Sciences “L. Sacco” Hospital, University of Milano Milan Italy",
    "National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital Bergen Norway",
    "Department of Clinical Medicine University of Bergen Bergen Norway",
    "Division of General Surgery, Department of Biomedical and Clinical Sciences “L. Sacco” Hospital, University of Milano Milan Italy"
  ],
  "article_type": "case study",
  "arxiv": null,
  "author_total": 6,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Cataletti Giovanni",
      "orcid": "0009-0009-4969-270X"
    },
    {
      "affs": [
        0
      ],
      "name": "Gridavilla Daniele"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Nylund Kim",
      "orcid": "0000-0001-8178-3614"
    },
    {
      "affs": [
        3
      ],
      "name": "Colombo Francesco"
    },
    {
      "affs": [
        3
      ],
      "name": "Danelli Piergiorgio"
    },
    {
      "affs": [
        0
      ],
      "name": "Maconi Giovanni",
      "orcid": "0000-0003-0810-4026"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0rre938q69ncm.bib",
  "cited_by": 0,
  "doi": "10.1002/jcu.70288",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13730177/",
  "id": "0rre938q69ncm",
  "issns": [
    "0091-2751",
    "1097-0096"
  ],
  "landing_url": "https://doi.org/10.1002/jcu.70288",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2711|Appendicitis Diagnosis and Management"
    ]
  ],
  "openalex": "W7165048372",
  "pdf_url": null,
  "pmcid": "PMC13730177",
  "pmid": "42304972",
  "published": "2026-06-17",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0rre938q69ncm.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:22:47Z",
      "native_id": "PMC13730177",
      "source": "pmc",
      "url": "https://doi.org/10.1002/jcu.70288"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2711|Appendicitis Diagnosis and Management",
      "subfield": "general"
    }
  ],
  "title": "Complicated Acute Appendicitis Conservatively Treated in Two Patients With Crohn's Disease: The Role of Intestinal Ultrasound and Contrast‐Enhanced Ultrasound",
  "title_text": "Complicated Acute Appendicitis Conservatively Treated in Two Patients With Crohn's Disease: The Role of Intestinal Ultrasound and Contrast‐Enhanced Ultrasound",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:22:47Z",
  "url": "https://research.draconitic.com/paper/0rre938q69ncm",
  "venue": "Journal of Clinical Ultrasound",
  "versions": []
}