{
  "abstract": "Revision total hip arthroplasty (THA) for persistent or unexplained pain remains controversial. Uncertainty remains regarding the subsequent risk of re-revision following revision THA for pain.\n\nThe objectives of this study are to compare the risk of all-cause and cause-specific re-revision following first-time revision THA performed for pain versus aseptic loosening.\n\nThis nationwide, register-based cohort study will use data from the Danish Hip Arthroplasty Register. Patients who underwent primary THA followed by first-time revision THA for pain or aseptic loosening between 1995 and 2025 will be included. Patients will be followed from the index revision until re-revision, death, emigration, or end of follow-up. The primary outcome is time to all-cause re-revision. Secondary outcomes are cause-specific re-revision due to pain, aseptic loosening, infection, or dislocation. Cumulative incidence will be estimated using competing-risk methods, and hazard ratios will be estimated using Cox proportional hazards regression.\n\nThe study will provide nationwide evidence on the risk of re-revision following revision THA for pain and may inform clinical decision-making and patient counselling.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Orthopedic Surgery and Traumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen."
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "P. P. Hald"
    },
    {
      "name": "S. M. Aljuboori"
    },
    {
      "name": "S. Overgaard"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0s3becbsy5d4h.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.09.09.26361766",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.09.09.26361766v1.full",
  "id": "0s3becbsy5d4h",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.09.09.26361766v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "orthopedics"
    ],
    [
      "openalex",
      "2746|Orthopaedic implants and arthroplasty"
    ]
  ],
  "openalex": "W7212314618",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.09.09.26361766v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-09",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0s3becbsy5d4h.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:19Z",
      "native_id": "10.64898/2026.09.09.26361766",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.09.09.26361766v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:orthopedics",
      "subfield": "surgery"
    }
  ],
  "title": "Prognosis of 1st time revision due to pain following primary total hip arthroplasty - a nationwide cohort study from the Danish Hip Arthroplasty Register",
  "title_text": "Prognosis of 1st time revision due to pain following primary total hip arthroplasty - a nationwide cohort study from the Danish Hip Arthroplasty Register",
  "type": "preprint",
  "updated_at": "2026-10-30T12:18:19Z",
  "url": "https://research.draconitic.com/paper/0s3becbsy5d4h",
  "venue": "medRxiv",
  "versions": []
}