{
  "abstract": "A straightforward and green synthetic method has been developed to prepare functionalized 2-arylbenzimidazole derivatives from readily accessible starting materials (arylmethyl alcohols and o-phenylenediamines) via a two-step, one-pot reaction. In the first step, arylmethyl alcohols are oxidized using MnO2 (4-8 equiv.) under both solvent-free and toluene-mediated conditions. subsequently, the aromatic aldehyde undergoes a 10 mol% iodine-catalyzed condensation with o-phenylenediamine in toluene at 100 °C under open-air conditions, leading to the production of 2-substituted benzimidazoles. The one-pot direct conversion of benzyl alcohols to 2-arylbenzimidazoles proceeds efficiently, affording the desired benzofused imidazoles in good to excellent yields, up to 91%. The sustainable method exhibits broad substrate scope, tolerating a wide range of functional groups. Mechanistic studies support a plausible imine formation pathway, followed by cyclization and oxidative aromatization under open-air conditions. This work highlights the synthetic utility and potential of the developed green method for future applications in organic synthesis and medicinal chemistry.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Industrial and Engineering Chemistry, Institute of Chemical Technology – IOC Bhubaneswar, IIT Kharagpur Extension Centre, Mouza Samantpuri, Bhubaneswar, Odisha, India, 751013",
    "Department of Chemistry",
    "National Institute of Technology Puducherry"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Savita Gat"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Selvam Vasanth"
    },
    {
      "affs": [
        0
      ],
      "name": "Jayshree Nandkumar Solanke"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Vasudevan Dhayalan",
      "orcid": "0000-0003-4548-2894"
    },
    {
      "affs": [
        0
      ],
      "name": "Rambabu Dandela"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0s728fs5k9z6k.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15008907/v1",
  "fulltext_url": null,
  "id": "0s728fs5k9z6k",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008907/v1",
  "language": null,
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Synthesis and Reactions of Organic Compounds"
    ]
  ],
  "openalex": "W7213242581",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15008907/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-16",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/0s728fs5k9z6k.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15008907",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15008907/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Synthesis and Reactions of Organic Compounds",
      "subfield": "organic"
    }
  ],
  "title": "A Simple and Green One-Pot Synthesis of 2-Arylbenzimidazoles from Alcohols Using MnO2/I2",
  "title_text": "A Simple and Green One-Pot Synthesis of 2-Arylbenzimidazoles from Alcohols Using MnO2/I2",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/0s728fs5k9z6k",
  "venue": "ChemRxiv",
  "versions": []
}