{
  "abstract": "Agri-food byproducts are increasingly recognized as sustainable feedstocks for high-value bioactive compounds; but their practical valorization requires integrated evidence on recovery conditions; chemical composition; bioactivity; and application readiness. This review critically examines green recovery strategies and chemical profiling platforms for bioactive compounds recovered from peels; pomace; seed residues; hulls; vegetation waters; and pruning waste. Emphasis is placed on how extraction variables shape chemical profiles; extract quality; and reported biological activities. Ultrasound- and microwave-assisted extraction; enzyme- and fermentation-assisted recovery; supercritical fluid extraction; pressurized liquid extraction; pulsed electric field-assisted pretreatment; and green solvent-based extraction are discussed in terms of target-compound selectivity; solvent and energy demand; process safety; scalability; and sustainability-related evidence. Chromatographic; mass-spectrometric; spectroscopic; and metabolomics-based profiling approaches are evaluated for identification; annotation; quantification; fingerprinting; quality-marker selection; and standardization; with confidence levels distinguished according to authentic-standard matching; tandem mass spectrometry evidence; spectral libraries; or fingerprint-level evidence. Circular valorization pathways in food; nutraceutical; cosmetic; pharmaceutical, and biopesticide-related applications are further considered with attention to feedstock heterogeneity; process standardization; stability; safety; regulatory feasibility; scalability; and techno-economic feasibility. Overall; this review provides a linkage-oriented framework for developing standardized; application-readiness-oriented bioactive candidates from agri-food byproducts.",
  "abstract_shown": true,
  "affiliations": [
    "Rural Development Administration",
    "National Institute of Crop Science"
  ],
  "article_type": "review",
  "arxiv": null,
  "author_total": 2,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Hyo Jun Won",
      "orcid": "0009-0006-5149-6060"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Ae‐Jin Choi",
      "orcid": "0000-0002-4700-4899"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0sxgzqbzbvynh.bib",
  "cited_by": 6,
  "doi": "10.3390/molecules31122136",
  "fulltext_url": null,
  "id": "0sxgzqbzbvynh",
  "issns": [
    "1420-3049",
    "1433-1373"
  ],
  "landing_url": "https://doi.org/10.3390/molecules31122136",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1106|Agricultural and Biological Research"
    ]
  ],
  "openalex": "W7165024906",
  "pdf_url": null,
  "pmcid": "PMC13305183",
  "pmid": "42357532",
  "published": "2026-06-17",
  "publisher": "Multidisciplinary Digital Publishing Institute",
  "ris": "https://research.draconitic.com/paper/0sxgzqbzbvynh.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:26:50Z",
      "native_id": "W7165024906",
      "source": "openalex",
      "url": "https://doi.org/10.3390/molecules31122136"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "issn:1420-3049",
      "subfield": "general"
    }
  ],
  "title": "From Agri-Food Byproducts to High-Value Bioactive Compounds: A Critical Review Linking Green Recovery and Chemical Profiling to Circular Valorization",
  "title_text": "From Agri-Food Byproducts to High-Value Bioactive Compounds: A Critical Review Linking Green Recovery and Chemical Profiling to Circular Valorization",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T13:21:09Z",
  "url": "https://research.draconitic.com/paper/0sxgzqbzbvynh",
  "venue": "Molecules",
  "versions": []
}