{
  "abstract": "Bangladesh is facing a major resurgence of measles, with more than 60,000 suspected cases and over 600 deaths reported between March and May 2026. Despite the growing outbreak, hospital-based evidence in Bangladesh remains limited regarding measles vaccination status and its association with clinical complications. To address this critical gap, our study aimed to assess the vaccination status and its relationship with the development of clinical complications. This cross-sectional study enrolled 260 children aged 2–72 months with clinically confirmed measles who were admitted to four dedicated measles treatment hospitals in Dhaka, Bangladesh, between 15 and 25 April 2026. Data on vaccination status, sociodemographic characteristics, feeding practices, nutritional status, clinical symptoms, and complications were collected through caregiver interviews and hospital records. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were estimated; p < 0.05 was considered statistically significant. Among enrolled children, 74.6% were unvaccinated, 18.8% were partially vaccinated, and only 6.5% were fully vaccinated. In the multivariable model, age below 9 months (aOR 0.09, 95% CI 0.03–0.268, p < 0.001) was independently associated with lower odds of vaccination, while household income at or above the median (aOR 3.983, 95% CI 1.8–8.813, p = 0.004) was associated with higher odds. Complications developed in 31.1% of cases, with respiratory involvement being most common. Absence of exclusive breastfeeding (aOR 2.336, 95% CI 1.027–5.313, p = 0.043) and presenting with exactly three symptoms at admission (aOR 3.106, 95% CI 1.274–7.572, p = 0.013) were independently associated with complications. Unvaccinated children had markedly higher odds of complications than vaccinated children (aOR 5.729, 95% CI: 2.363–13.889, p < 0.001). The heavy burden of measles among unvaccinated children, shaped by socioeconomic disadvantage and suboptimal feeding practices, underscores the urgent need to restore immunization coverage and strengthen equitable health services in Bangladesh.",
  "abstract_shown": true,
  "affiliations": [
    "Public Health Promotion and Development Society, Dhaka, Bangladesh",
    "Eastern Medical College, Kabila, Cumilla, Bangladesh",
    "Department of Public Health, North South University, Dhaka, Bangladesh",
    "International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh",
    "Directorate General of Health Services (DGHS), Dhaka, Bangladesh",
    "Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Thailand",
    "Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom",
    "Ibn Sina Medical College Hospital, Dhaka, Bangladesh",
    "BRAC James P Grant School of Public Health, BRAC University, Dhaka, Bangladesh",
    "Division of Clinical and Translational Research, Department of Medicine, McGill University, Canada",
    "World Health Organization, Dhaka, Bangladesh",
    "NSU Global Health Institute (NGHI), North South University, Dhaka, Bangladesh"
  ],
  "article_type": "Research Article",
  "arxiv": null,
  "author_total": 14,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Arpita Goutam"
    },
    {
      "affs": [
        1
      ],
      "name": "Anamul Hasan"
    },
    {
      "affs": [
        2
      ],
      "name": "Md Abdullah Saeed Khan"
    },
    {
      "affs": [
        3
      ],
      "name": "Mohammad Ali Hossain Mahid"
    },
    {
      "affs": [
        4
      ],
      "name": "Sumaya Binte Masud"
    },
    {
      "affs": [
        5
      ],
      "name": "Habiba Babul"
    },
    {
      "affs": [
        6
      ],
      "name": "Lamisa Rahman"
    },
    {
      "affs": [
        7
      ],
      "name": "Amina Siddiqui"
    },
    {
      "affs": [
        8
      ],
      "name": "Salma Tasnim Luthfa"
    },
    {
      "affs": [
        9
      ],
      "name": "Samiha Nahar Tuli"
    },
    {
      "affs": [
        10
      ],
      "name": "Indrani Paul"
    },
    {
      "affs": [
        11
      ],
      "name": "M. Rashidul Bari"
    },
    {
      "name": "Abu Sayeed Md Saleh"
    },
    {
      "name": "Mohammad Delwer Hossain Hawlader"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0tygp7yy9hz9v.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pone.0353336",
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  "id": "0tygp7yy9hz9v",
  "issns": [
    "1932-6203"
  ],
  "landing_url": "https://doi.org/10.1371/journal.pone.0353336",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "plos",
      "/Biology and life sciences/Immunology/Vaccination and immunization"
    ],
    [
      "plos",
      "/Biology and life sciences/Immunology/Vaccination and immunization/Vaccine development"
    ],
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      "/Biology and life sciences/Microbiology/Virology/Viral vaccines"
    ],
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      "/Medicine and health sciences/Health care/Caregivers"
    ],
    [
      "plos",
      "/Medicine and health sciences/Immunology/Vaccination and immunization"
    ],
    [
      "plos",
      "/Medicine and health sciences/Immunology/Vaccination and immunization/Vaccine development"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Infectious diseases/Infectious disease control/Vaccines"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Infectious diseases/Infectious disease control/Vaccines/Viral vaccines"
    ],
    [
      "plos",
      "/Medicine and health sciences/Medical conditions/Infectious diseases/Viral diseases/Measles"
    ],
    [
      "plos",
      "/Medicine and health sciences/Pediatrics/Neonatology/Breast feeding"
    ],
    [
      "plos",
      "/Medicine and health sciences/Public and occupational health/Preventive medicine/Vaccination and immunization"
    ],
    [
      "plos",
      "/Medicine and health sciences/Public and occupational health/Preventive medicine/Vaccination and immunization/Vaccine development"
    ],
    [
      "plos",
      "/Medicine and health sciences/Women's health/Maternal health/Breast feeding"
    ],
    [
      "plos",
      "/People and places/Geographical locations/Asia/Bangladesh"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-11-11",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/0tygp7yy9hz9v.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T12:20:55Z",
      "native_id": "10.1371/journal.pone.0353336",
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      "url": "https://doi.org/10.1371/journal.pone.0353336"
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  "subjects": [
    {
      "field": "biology",
      "origin": "plos:immunology",
      "subfield": "immunology"
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    {
      "field": "medicine",
      "origin": "plos:infectious diseases",
      "subfield": "infectious-disease"
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    {
      "field": "medicine",
      "origin": "plos:pediatrics",
      "subfield": "reproductive-child"
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  ],
  "title": "Vaccination status and its association with complications among the patients admitted with measles in the dedicated measles hospitals, Dhaka, Bangladesh",
  "title_text": "Vaccination status and its association with complications among the patients admitted with measles in the dedicated measles hospitals, Dhaka, Bangladesh",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T12:20:02Z",
  "url": "https://research.draconitic.com/paper/0tygp7yy9hz9v",
  "venue": "PLOS One",
  "versions": []
}