{
  "abstract": "Introduction\n\nCoronary artery disease (CAD) is a multifactorial condition influenced by both genetic predispositions and environmental exposures.Case description\n\nWe present a pair of male monozygotic twins diagnosed with identical critical left anterior descending artery stenosis, suggesting a possible hereditary susceptibility involving this coronary segment. One twin presented with acute coronary syndrome while the other was diagnosed with CAD during screening prompted by his sibling's diagnosis.Conclusion\n\nThis report underscores the importance of early screening among genetically related individuals and contributes to the understanding of phenotypic variability in genetically identical patients with CAD.Learning points\n\nThere is a strong genetic contribution to the anatomical distribution of CAD even when environmental risk factors differ between twins.Thorough cardiovascular risk assessment and management are warranted for asymptomatic identical twins when their co-twin presents with CAD. Early screening for subclinical disease and the consideration of advanced imaging modalities may be justified in this context.",
  "abstract_shown": true,
  "affiliations": [
    "Geriatrics Division, Sheba Medical Center, Ramat-Gan, Israel.",
    "Gray Faculty of Medical and Health Sciences, Tel-Aviv University, Israel.",
    "Cardiology Division, Sheba Medical Center, Ramat-Gan, Israel.",
    "Cardiology Division, Lady Davis Carmel Medical Center, Haifa, Israel.",
    "Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Aya Cohen"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Dan Justo"
    },
    {
      "affs": [
        1,
        2
      ],
      "name": "Israel Barabash"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Keren Zisman"
    },
    {
      "affs": [
        3,
        4
      ],
      "name": "Asaf Danon"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0x4ybhd7shm9y.bib",
  "cited_by": 0,
  "doi": "10.12890/2026_007079",
  "fulltext_url": "https://europepmc.org/articles/PMC13750774",
  "id": "0x4ybhd7shm9y",
  "issns": [
    "2284-2594"
  ],
  "landing_url": "https://europepmc.org/article/MED/43012031",
  "language": "eng",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2705|Coronary Artery Anomalies"
    ]
  ],
  "openalex": "W7223696345",
  "pdf_url": "https://europepmc.org/articles/PMC13750774?pdf=render",
  "pmcid": "PMC13750774",
  "pmid": "43012031",
  "published": "2026-10-26",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0x4ybhd7shm9y.ris",
  "sources": [
    {
      "first_seen": "2026-11-12T15:25:13Z",
      "native_id": "MED:43012031",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/43012031"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2705|Coronary Artery Anomalies",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Identical Critical Left Anterior Descending Artery Stenosis in Monozygotic Twins.",
  "title_text": "Identical Critical Left Anterior Descending Artery Stenosis in Monozygotic Twins.",
  "type": "peer-reviewed",
  "updated_at": "2026-11-13T03:21:10Z",
  "url": "https://research.draconitic.com/paper/0x4ybhd7shm9y",
  "venue": "European journal of case reports in internal medicine",
  "versions": []
}