{
  "abstract": "Vaginal agenesis is a congenital condition of the female genital tract. Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a disorder characterised by agenesis of Mullerian structures, including the uterus and upper two-thirds of the vagina, with normally developed secondary sexual characteristics. The author presents a case of a 21-year-old married woman with primary amenorrhoea diagnosed with type 1 MRKH syndrome. The patient underwent the modified McIndoe vaginoplasty procedure with the use of a human amnion as a graft for creating a neovagina. The patient was discharged fifteen days postsurgery with training on the use of vaginal dilators. The patient was followed up weekly to assess vaginal patency. At the end of three months, the patient had approximately 7 cm of neovaginal length.Sexual intercourse was recommended thereafter.Modified McIndoe vaginoplasty with a human amnion graft is an effective, simple, safe procedure with high acceptability and a good enough functional vagina in women with MRKH syndrome.",
  "abstract_shown": true,
  "affiliations": [
    "Professor and Head, Department of Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India.",
    "Associate Professor, Department of Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India.",
    "Research Assistant, Department of Central Research Facility, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India."
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hemant Deshpande"
    },
    {
      "affs": [
        1
      ],
      "name": "Shriraj Katakdhond"
    },
    {
      "affs": [
        2
      ],
      "name": "Abira Ghosh"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0xnkzyje4bn43.bib",
  "cited_by": 0,
  "doi": "10.7860/jcdr/2026/92046.24659",
  "fulltext_url": "https://jcdr.net/articles/PDF/24659/92046_CE[Ra1]_F(KR)_PF1(Rf_NK)redo_PFA_NC(SS)_PN(IS).pdf",
  "id": "0xnkzyje4bn43",
  "issns": [
    "2249-782X",
    "0973-709X"
  ],
  "landing_url": "https://doi.org/10.7860/jcdr/2026/92046.24659",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "2729|Gynecological conditions and treatments"
    ]
  ],
  "openalex": "W7223169620",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "JCDR Research and Publications Private Limited",
  "ris": "https://research.draconitic.com/paper/0xnkzyje4bn43.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:44:41Z",
      "native_id": "a98cebc16bf943b8a33b43368ee753fc",
      "source": "doaj",
      "url": "https://doi.org/10.7860/jcdr/2026/92046.24659"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2729|Gynecological conditions and treatments",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Human Amnion Grafting for Vaginal Agenesis in Mayer-Rokitansky-Kuster-Hauser Syndrome: A Case Report",
  "title_text": "Human Amnion Grafting for Vaginal Agenesis in Mayer-Rokitansky-Kuster-Hauser Syndrome: A Case Report",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:44:41Z",
  "url": "https://research.draconitic.com/paper/0xnkzyje4bn43",
  "venue": "Journal of Clinical and Diagnostic Research",
  "versions": []
}