{
  "abstract": "Poorly validated antibodies generate misleading results and waste research resources. Two new studies in PLOS Biology quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.\n\nPoorly validated antibodies generate misleading results and waste research resources. This Primer explores two new studies in PLOS Biology that quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.",
  "abstract_shown": true,
  "affiliations": [
    "Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU), LMU Open Science Center (OSC), German Center for Cardiovascular Research (DZHK), Munich, Germany"
  ],
  "article_type": "Primer",
  "arxiv": null,
  "author_total": 1,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Johan Duchêne"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0y8tmbqrrjxyb.bib",
  "cited_by": 0,
  "doi": "10.1371/journal.pbio.3004001",
  "fulltext_url": "https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3004001",
  "id": "0y8tmbqrrjxyb",
  "issns": [
    "1545-7885"
  ],
  "landing_url": "https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3004001",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2741|Monoclonal and Polyclonal Antibodies Research"
    ],
    [
      "plos",
      "/Biology and life sciences/Biochemistry/Proteins/Immune system proteins/Antibodies/Antibody specificity"
    ],
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      "plos",
      "/Biology and life sciences/Ecology/Ecosystems"
    ],
    [
      "plos",
      "/Biology and life sciences/Immunology/Immune system proteins/Antibodies/Antibody specificity"
    ],
    [
      "plos",
      "/Biology and life sciences/Molecular biology/Molecular biology techniques/Molecular biology assays and analysis techniques/Gene expression and vector techniques/Protein expression"
    ],
    [
      "plos",
      "/Biology and life sciences/Physiology/Immune physiology/Antibodies/Antibody specificity"
    ],
    [
      "plos",
      "/Computer and information sciences/Computer vision/Target detection"
    ],
    [
      "plos",
      "/Ecology and environmental sciences/Ecology/Ecosystems"
    ],
    [
      "plos",
      "/Medicine and health sciences/Immunology/Immune system proteins/Antibodies/Antibody specificity"
    ],
    [
      "plos",
      "/People and places/Population groupings/Professions/Scientists"
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    [
      "plos",
      "/Research and analysis methods/Molecular biology techniques/Molecular biology assays and analysis techniques/Gene expression and vector techniques/Protein expression"
    ],
    [
      "plos",
      "/Research and analysis methods/Research assessment/Reproducibility"
    ],
    [
      "plos",
      "/Research and analysis methods/Research assessment/Research validity"
    ],
    [
      "plos",
      "/Science policy/Research integrity/Research ethics"
    ],
    [
      "plos",
      "/Science policy/Science and technology workforce/Careers in research/Scientists"
    ]
  ],
  "openalex": "W7220858464",
  "pdf_url": "https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3004001&type=printable",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-07",
  "publisher": "Public Library of Science",
  "ris": "https://research.draconitic.com/paper/0y8tmbqrrjxyb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:30Z",
      "native_id": "10.1371/journal.pbio.3004001",
      "source": "plos",
      "url": "https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3004001"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "plos:molecular biology",
      "subfield": "molecular-biology"
    },
    {
      "field": "biology",
      "origin": "plos:ecology",
      "subfield": "ecology"
    },
    {
      "field": "biology",
      "origin": "plos:immunology",
      "subfield": "immunology"
    }
  ],
  "title": "Better antibodies, better science",
  "title_text": "Better antibodies, better science",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:30Z",
  "url": "https://research.draconitic.com/paper/0y8tmbqrrjxyb",
  "venue": "PLOS Biology",
  "versions": []
}