{
  "abstract": "Suppression of recombination on the Y chromosome maintains linkage between male-specific loci and is commonly established by inversions. Here, we describe a young, inversion-free Y chromosome (neo-Y) in Drosophila albomicans with a unique history and paradoxical signature of exchange. Prior to recombination shutdown in males, it repeatedly recombined with the X-linked counterpart (neo-X) but at the same time preserved complete long-range linkage of the chromosome ends. By assembling multiple neo-Ys chromosomes and QTL-mapping, we show that double crossovers maintained linkage between the male-sex determining region at one end to sexually antagonistic alleles and a locus essential for spermatogenesis at the other. We argue that such long-range linkage of distal sex-specific loci disfavors inversions but instead encourages the emergence of achiasmy.",
  "abstract_shown": true,
  "affiliations": [
    "University of British Columbia"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "name": "M. Wang"
    },
    {
      "name": "M. Akhavizadegan"
    },
    {
      "name": "J.-Y. Wang"
    },
    {
      "name": "C.-H. Chang"
    },
    {
      "affs": [
        0
      ],
      "name": "K. H.-C. Wei"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/0zp6f0k72znyp.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.08.31.748364",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.08.31.748364v1.full",
  "id": "0zp6f0k72znyp",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.08.31.748364v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "evolutionary biology"
    ],
    [
      "openalex",
      "1311|Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities"
    ]
  ],
  "openalex": "W7208763607",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.08.31.748364v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-08-31",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/0zp6f0k72znyp.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:30Z",
      "native_id": "10.64898/2026.08.31.748364",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.08.31.748364v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:evolutionary biology",
      "subfield": "evolutionary-biology"
    }
  ],
  "title": "Long-range linkage maintained male-specific loci on a young Y chromosome prior to recombination shutdown",
  "title_text": "Long-range linkage maintained male-specific loci on a young Y chromosome prior to recombination shutdown",
  "type": "preprint",
  "updated_at": "2026-10-30T12:19:30Z",
  "url": "https://research.draconitic.com/paper/0zp6f0k72znyp",
  "venue": "bioRxiv",
  "versions": []
}