{
  "abstract": "Objectives\n\nPyogenic brain abscess is a life-threatening intracranial infection requiring timely diagnosis and coordinated medical-surgical management. Regional data from the Gulf area remains scarce.Methods\n\nWe retrospectively analyzed demographic, clinical, microbiological, management, and outcome data from adults diagnosed with pyogenic brain abscess based on clinical presentation and neuroimaging findings at Hamad Medical Corporation, Qatar, between 2015 and 2023. Outcomes were categorized using the Glasgow Outcome Scale (GOS) as favorable (GOS 4-5) or unfavorable (GOS 1-3).Results\n\nForty-eight patients were included; 41/48 (85%) were male, with a median age of 34 years. Common comorbidities and predisposing conditions included diabetes mellitus, otitis/mastoiditis, and sinusitis. A microbiological diagnosis was established in 35/48 (73%) patients. The most frequently isolated pathogens were the Streptococcus anginosus group, Staphylococcus aureus, and Klebsiella pneumoniae. Surgical intervention was performed in 38/48 (79%) patients, and 35/48 (73%) achieved a favorable outcome. In unadjusted analyses, recent neurosurgical procedures and Gram-negative infections were more frequent among patients with unfavorable outcomes. These patients had lower baseline Glasgow Coma Scale scores and more frequently presented with altered consciousness.Conclusion\n\nIn unadjusted analyses, favorable outcomes were more frequent among patients who underwent surgical intervention and those presenting with preserved consciousness. However, causality cannot be inferred.",
  "abstract_shown": true,
  "affiliations": [
    "Division of Infectious Diseases, Department of Internal Medicine, Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar.",
    "Department of Internal Medicine, Hamad Medical Corporation, Doha, Qatar.",
    "Department of Neurosurgery, Hamad Medical Corporation, Doha, Qatar.",
    "Qatar University College of Medicine, Doha, Qatar."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Sabeen Zara"
    },
    {
      "affs": [
        0
      ],
      "name": "Sara Al Balushi"
    },
    {
      "affs": [
        0
      ],
      "name": "Junais Koleri"
    },
    {
      "affs": [
        1
      ],
      "name": "Afia Aziz"
    },
    {
      "affs": [
        1
      ],
      "name": "Soubiya Ansari"
    },
    {
      "affs": [
        2
      ],
      "name": "Mu'ath Hussein"
    },
    {
      "affs": [
        0
      ],
      "name": "Aseel H Alzibdeh"
    },
    {
      "affs": [
        2
      ],
      "name": "Ahmed Saleh"
    },
    {
      "affs": [
        0
      ],
      "name": "Waqar Munir"
    },
    {
      "affs": [
        0,
        3
      ],
      "name": "Ali S Omrani"
    },
    {
      "affs": [
        0
      ],
      "name": "Muna Al Maslamani"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/12x9a1pxr22yx.bib",
  "cited_by": 0,
  "doi": "10.1016/j.ijregi.2026.101035",
  "fulltext_url": "https://europepmc.org/articles/PMC13694896",
  "id": "12x9a1pxr22yx",
  "issns": [
    "2772-7076"
  ],
  "landing_url": "https://europepmc.org/article/MED/42927205",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Infectious Diseases and Tuberculosis"
    ]
  ],
  "openalex": "W7220463399",
  "pdf_url": "https://europepmc.org/articles/PMC13694896?pdf=render",
  "pmcid": "PMC13694896",
  "pmid": "42927205",
  "published": "2026-10-05",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/12x9a1pxr22yx.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:21:18Z",
      "native_id": "MED:42927205",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42927205"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Infectious Diseases and Tuberculosis",
      "subfield": "surgery"
    }
  ],
  "title": "Pyogenic brain abscesses in Qatar: A national retrospective observational study.",
  "title_text": "Pyogenic brain abscesses in Qatar: A national retrospective observational study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:21:18Z",
  "url": "https://research.draconitic.com/paper/12x9a1pxr22yx",
  "venue": "IJID regions",
  "versions": []
}