{
  "abstract": "ImportanceDyslipidemia, hypertension, and diabetes are highly prevalent conditions for which medical nutrition therapy (MNT) is guideline-recommended, yet access remains limited, and real-world evidence on technology-enabled MNT models at scale is sparse.\n\nObjectiveTo characterize lipid, blood pressure, and glycemic outcomes among adults receiving virtual MNT (vMNT) across three cardiometabolic conditions.\n\nDesignRetrospective cohort study of adults with a first Nourish appointment before November 2025, followed for 6 months.\n\nSettingNational vMNT platform.\n\nParticipantsAdults meeting enrollment criteria for dyslipidemia, hypertension, or diabetes and remaining engaged in care with [≥]1 follow-up measurement at 3 or 6 months. Final cohorts: dyslipidemia (n=6,501), hypertension (n=13,704), diabetes (n=2,444); 18,965 unique patients overall.\n\nExposurevMNT delivered by a registered dietitian via telehealth visits, with technology-enabled support between visits.\n\nMain Outcomes and MeasuresOutcomes were LDL cholesterol, total cholesterol, HDL cholesterol, and triglycerides (dyslipidemia); systolic and diastolic blood pressure (SBP, DBP) (hypertension); and HbA1c (diabetes), assessed at enrollment, 3, and 6 months. Weight was a secondary outcome. The proportion achieving guideline-recommended targets (HbA1c <7.0%, SBP <130 mmHg) was also assessed.\n\nResultsAmong 18,965 patients (mean [SD] age, 42.9 [11.6] years; 15,770 [83.2%] female), significant changes from baseline to 6 months included: LDL cholesterol (-14.0 mg/dL [SE, 0.56]); total cholesterol (-19.4 mg/dL [SE, 0.61]); HDL cholesterol (-0.5 mg/dL [SE, 0.15]); triglycerides (-28.6 mg/dL [SE, 1.06]); SBP (-5.5 mmHg [SE, 0.16]); DBP (-4.5 mmHg [SE, 0.11]); and HbA1c (-1.37 percentage points [SE, 0.04]) (all P<.001). Among those with elevated SBP, 57.3% achieved <130 mmHg by 6 months; among those with elevated HbA1c, 54.7% achieved <7.0%. Outcomes among patients with stable medication regimens were similar to the full cohort.\n\nConclusions and RelevanceIn this study of 18,965 patients, vMNT delivered through a technology-enabled care model was associated with clinically meaningful improvement across three prevalent cardiometabolic conditions. These findings support technology-enabled virtual care as a scalable approach to delivering effective MNT.",
  "abstract_shown": true,
  "affiliations": [
    "Nourish Inc"
  ],
  "article_type": "PUBLISHAHEADOFPRINT",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "R. N. Adams"
    },
    {
      "name": "D. Mozaffarian"
    },
    {
      "name": "C. Bollinger"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/12zw9a89kdsp9.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.01.26364516",
  "fulltext_url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364516v1.full",
  "id": "12zw9a89kdsp9",
  "issns": [],
  "landing_url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364516v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "medrxiv",
      "nutrition"
    ],
    [
      "openalex",
      "2739|Telemedicine and Telehealth Implementation"
    ]
  ],
  "openalex": "W7220441496",
  "pdf_url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364516v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-01",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/12zw9a89kdsp9.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:06Z",
      "native_id": "10.64898/2026.10.01.26364516",
      "source": "medrxiv",
      "url": "https://www.medrxiv.org/content/10.64898/2026.10.01.26364516v1"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "medrxiv:nutrition",
      "subfield": "nutrition"
    }
  ],
  "title": "Real-World Outcomes of Virtual Medical Nutrition Therapy in Dyslipidemia, Hypertension, or Diabetes",
  "title_text": "Real-World Outcomes of Virtual Medical Nutrition Therapy in Dyslipidemia, Hypertension, or Diabetes",
  "type": "preprint",
  "updated_at": "2026-10-30T12:20:06Z",
  "url": "https://research.draconitic.com/paper/12zw9a89kdsp9",
  "venue": "medRxiv",
  "versions": []
}