{
  "abstract": "Background: Maternal comorbidities and their relationship with fetal outcomes are a key public health concern. Although the aetiology of many congenital anomalies (CA) is unknown, maternal characteristics may influence their occurrence and the need for hospitalization.\n\nAim: to describe comorbidities and procedures recorded in hospitalization records of pregnant women whose children had CA\n\nMethods: Cross-sectional study was performed in pregnant women, residents in Valencian Region (VR, Spain), who had children between 2007-2022, live or stillbirths and diagnosed with CA, and who had at least one hospitalization during pregnancy. Pregnant women were identified from the CA population-based registry of VR, and their hospitalizations from the Hospital Discharge Database between 2006-2023. Descriptive analysis of hospitalisations characteristics was performed overall and by trimester of pregnancy\n\nResults: 13711 hospitalizations were recorded among 10884 pregnant women, who had 10974 children with CA. The median number of diagnoses was 5, 95.5% had any diagnosis included in a specific chapter of pregnancy. In first trimester, 59.5% did not have diagnoses in this specific chapter and the main diagnosis was related to assisted reproductive fertility. Diabetes (8.7%) and hypertension (5.5%) were the most frequent comorbidities. The median number of procedures per hospitalization was 3; 87.5% were obstetric and 32.2% cesarean sections. Main diagnosis and procedure in hospitalizations that required ICU were preeclampsia (44.4%) and cesarean (87.7%). Pregnant women group with children with congenital heart defects had more surgical procedure proportion (than other CA) with statistical differences\n\nConclusions: Early diagnoses related to fertility problems highlight the need for enhanced monitoring from the first trimester. Integrating population-based and hospital data would strengthen surveillance and improve understanding of factors associated with CA and maternal hospitalization\n\nKey messages: • Pregnancies affected by congenital anomalies show a high burden of maternal comorbidities and procedures, with hospitalizations largely obstetric and varying by trimester.\n\n• Integrating population-based registries with hospital data strengthens public health surveillance and supports earlier identification of maternal risks and improved care planning.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "abstract",
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "name": "L Garcia-Villodre"
    },
    {
      "name": "L Barrachina-Bonet"
    },
    {
      "name": "B Arribas-Díaz"
    },
    {
      "name": "L Páramo-Rodríguez"
    },
    {
      "name": "A Torró-Gómez"
    },
    {
      "name": "N García-Flores"
    },
    {
      "name": "P Oña-Nieto"
    },
    {
      "name": "O Zurriaga"
    },
    {
      "name": "JV Sorlí"
    },
    {
      "name": "C Cavero-Cabornell"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/130b7z64jycf8.bib",
  "cited_by": 0,
  "doi": "10.1093/eurpub/ckag169.299",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13697351/",
  "id": "130b7z64jycf8",
  "issns": [
    "1101-1262",
    "1464-360X"
  ],
  "landing_url": "https://doi.org/10.1093/eurpub/ckag169.299",
  "language": "en",
  "licence": "CC-BY-NC-4.0",
  "licence_label": "CC BY-NC 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "3. PARALLEL PROGRAMME"
    ],
    [
      "heading",
      "AcademicSubjects/MED00860"
    ],
    [
      "heading",
      "AcademicSubjects/SOC01210"
    ],
    [
      "heading",
      "AcademicSubjects/SOC02610"
    ],
    [
      "openalex",
      "2746|Congenital Anomalies and Fetal Surgery"
    ]
  ],
  "openalex": "W7223656866",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13697351/pdf/?tool=EBI",
  "pmcid": "PMC13697351",
  "pmid": null,
  "published": "2026-10-01",
  "publisher": "Oxford University Press",
  "ris": "https://research.draconitic.com/paper/130b7z64jycf8.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:18:25Z",
      "native_id": "PMC13697351",
      "source": "pmc",
      "url": "https://doi.org/10.1093/eurpub/ckag169.299"
    },
    {
      "first_seen": "2026-10-30T12:21:31Z",
      "native_id": "PMC:PMC13697351",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13697351"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Congenital Anomalies and Fetal Surgery",
      "subfield": "surgery"
    }
  ],
  "title": "Comorbidity and hospital procedures in pregnancies with congenital anomalies: population-based study",
  "title_text": "Comorbidity and hospital procedures in pregnancies with congenital anomalies: population-based study",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:34:24Z",
  "url": "https://research.draconitic.com/paper/130b7z64jycf8",
  "venue": "The European Journal of Public Health",
  "versions": []
}