{
  "abstract": "Background: Patients presenting with acute myocardial infarction (MI) represent a high-risk population after percutaneous coronary intervention (PCI), characterized by plaque instability, residual thrombus burden, and heightened ischemic and bleeding risk. However, the time-dependent risk profile and long-term durability of stent-related outcomes according to MI status have not been characterized for the Ultimaster TM biodegradable-polymer sirolimus-eluting stent (BP-SES). We evaluated clinical outcomes according to MI status using a 1-month landmark approach.\n\nMethods: In this prospective, multicenter Korean registry, 932 patients who underwent PCI with the Ultimaster TM or Ultimaster TM Tansei TM BP-SES were stratified into MI ( n = 346) and non-MI ( n = 586) groups. The primary endpoint was net adverse clinical events (NACE), a composite of cardiac death, MI, cerebrovascular accident, bleeding, and definite or probable stent thrombosis, assessed at 1 month, at 1 year, and from 1 month to 3 years using a 1-month landmark analysis.\n\nResults: At 1 month, NACE was significantly higher in the MI group [12.1% vs. 7.0%; hazard ratio [HR] 1.66, 95% confidence interval [CI] 1.01–2.72; p = 0.045], driven primarily by numerical excesses in cardiac death and bleeding. At 1 year, the cumulative incidence of NACE was numerically higher in the MI group (20.5% vs. 14.9%), a relative difference of approximately 40% without statistical significance, and 1-year target lesion failure was low and comparable (7.2% vs. 5.3%; p = 0.482). In the 1-month landmark analysis evaluating events from 1 month to 3 years, no significant differences were observed for any endpoint, including NACE (12.4% vs. 13.3%; HR 0.84, 95% CI 0.55–1.29; p = 0.425).\n\nConclusion: The early excess of clinical events in MI patients undergoing PCI with the Ultimaster TM BP-SES did not extend beyond the first month, and no significant differences in outcomes through 3 years were detected compared with non-MI patients. These findings suggest that, in the era of contemporary BP-SES and contemporary secondary prevention, MI status itself does not appear to be a major determinant of long-term outcomes after PCI, and are reassuring for the use of BP-SES across the spectrum of clinical presentations.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Cardiology, St. Vincent’s Hospital, The Catholic University of Korea",
    "Catholic Research Institute for Intractable Cardiovascular Disease (CRID), College of Medicine, The Catholic University of Korea",
    "Department of Cardiology, Soonchunhyang University Cheonan Hospital",
    "Department of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine",
    "Division of Cardiology, Department of Internal Medicine, Dankook University Hospital",
    "Department of Cardiology in Internal Medicine, Chungnam National University Hospital",
    "Department of Cardiology in Internal Medicine, Good Samsun Hospital",
    "Department of Cardiology, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 11,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Ki-Dong Yoo"
    },
    {
      "affs": [
        2
      ],
      "name": "Hun-Joo Lee"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Sang-Suk Choi"
    },
    {
      "affs": [
        3
      ],
      "name": "Gyung-Min Park"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jin Jung"
    },
    {
      "affs": [
        4
      ],
      "name": "Seong-Hoon Lim"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Sung-Ho Her"
    },
    {
      "affs": [
        5
      ],
      "name": "Jae-Hwan Lee"
    },
    {
      "affs": [
        2
      ],
      "name": "Seung Jin Lee"
    },
    {
      "affs": [
        6
      ],
      "name": "Jang-Whan Bae"
    },
    {
      "affs": [
        1,
        7
      ],
      "name": "Kyusup Lee"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/144z0jccc6bh6.bib",
  "cited_by": 0,
  "doi": "10.3389/fcvm.2026.1903710",
  "fulltext_url": null,
  "id": "144z0jccc6bh6",
  "issns": [
    "2297-055X"
  ],
  "landing_url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1903710/full",
  "language": null,
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [],
  "openalex": null,
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-30",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/144z0jccc6bh6.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:34:24Z",
      "native_id": "10.3389/fcvm.2026.1903710",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fcvm.2026.1903710/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2297-055X",
      "subfield": "cardiovascular"
    }
  ],
  "title": "Impact of myocardial infarction status on long-term outcomes after PCI with the ultimaster biodegradable-polymer sirolimus-eluting stent",
  "title_text": "Impact of myocardial infarction status on long-term outcomes after PCI with the ultimaster biodegradable-polymer sirolimus-eluting stent",
  "type": "peer-reviewed",
  "updated_at": "2026-11-01T00:21:04Z",
  "url": "https://research.draconitic.com/paper/144z0jccc6bh6",
  "venue": "Frontiers in Cardiovascular Medicine",
  "versions": []
}