{
  "abstract": "The growing use of artificial intelligence in the healthcare sector has facilitated the emergence of sophisticated clinical data analytics, but the most critical issues pertain to data privacy, model interpretability, and model trustworthiness. These problems still pose a challenge to its real-world application. This study proposes an interpretation of a deep learning framework for secure clinical data analytics. This proposes a privacy-preserving distributed learning framework in combination with a naturally interpretable model structure. The suggested framework enables parallel training across several healthcare facilities without compromising raw patient information, thereby keeping the data confidential without adversely affecting the analysis. An idea-driven deep learning framework is also presented to produce clinically significant intermediate representations that enable clear, interpretable predictions. Moreover, a new explanation stability mechanism is established to maintain the consistency and reliability of model explanations in distributed environments. To promote clinical safety, the decision module includes uncertainty to enable the system to detect predictions with low confidence and defer them to experts. Massive tests using actual clinical data on patient conditions can be conducted to demonstrate that the framework presented is much more successful than other methods with respect to predictiveness, interpretability, explanation stability, fairness, and calibration. Furthermore, the framework demonstrates that privacy preservation, interpretability, explanation reliability, and clinical usability can be jointly optimized within a unified learning architecture. The findings indicate the effectiveness of the suggested strategy in providing secure, transparent, and reliable clinical decision support, rendering it an appropriate strategy to implement in contemporary healthcare systems.",
  "abstract_shown": true,
  "affiliations": [
    "School of Computing, Horizon University College",
    "Department of Information Technology, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University",
    "Department of Computer Science, Faculty of Information Technology, Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University",
    "Department of Information Technology, College of Engineering and Computing, Liwa University",
    "Computer and Network Engineering Department, College of Computing, Umm Al-Qura University",
    "Department of Electronics and Communication Engineering, Cambridge Institute of Technology",
    "School of Engineering and IT, Manipal Academy of Higher Education"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Mahmoud Ahmad Al-Khasawneh"
    },
    {
      "affs": [
        1
      ],
      "name": "Deema Mohammed Alsekait"
    },
    {
      "affs": [
        2
      ],
      "name": "Kholoud Alkayid"
    },
    {
      "affs": [
        3
      ],
      "name": "Omar Kassem Khalil"
    },
    {
      "affs": [
        4
      ],
      "name": "Abdulghani Bakur Alsayegh"
    },
    {
      "affs": [
        4
      ],
      "name": "Amar Y. Jaffar"
    },
    {
      "affs": [
        5
      ],
      "name": "P. Karthik"
    },
    {
      "affs": [
        6
      ],
      "name": "K. M. Baalamurugan"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/149f6t34ypsaz.bib",
  "cited_by": 0,
  "doi": "10.1038/s41598-026-62055-8",
  "fulltext_url": "https://doi.org/10.1038/s41598-026-62055-8",
  "id": "149f6t34ypsaz",
  "issns": [
    "2045-2322"
  ],
  "landing_url": "https://doi.org/10.1038/s41598-026-62055-8",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "Q"
    ],
    [
      "lcc",
      "R"
    ],
    [
      "openalex",
      "1702|Explainable Artificial Intelligence (XAI)"
    ]
  ],
  "openalex": "W7170071695",
  "pdf_url": "https://www.nature.com/articles/s41598-026-62055-8_reference.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Nature Portfolio",
  "ris": "https://research.draconitic.com/paper/149f6t34ypsaz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:45:53Z",
      "native_id": "78640c0e5cbe46d38c552b12bcb08df4",
      "source": "doaj",
      "url": "https://doi.org/10.1038/s41598-026-62055-8"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "lcc:R",
      "subfield": "general"
    }
  ],
  "title": "Interpretable deep learning framework for secure clinical data analytics",
  "title_text": "Interpretable deep learning framework for secure clinical data analytics",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:45:53Z",
  "url": "https://research.draconitic.com/paper/149f6t34ypsaz",
  "venue": "Scientific Reports",
  "versions": []
}