{
  "abstract": "BackgroundEnvironmental exposures are emerging as major contributors to pulmonary disease yet remain under characterized compared with traditional air pollutants. This review aims to synthesize the major sources, exposure routes, toxicokinetic, detection methods, disease outcomes, regulatory status, knowledge gaps, and top research priorities for: microplastics, per- and polyfluoroalkyl substances, indoor air pollutants, and pesticides.MethodsThis paper selected multiple original research and regulatory sources based on selected keywords related to emerging environmental exposures and pulmonary outcomes.ResultsAcross the exposures, pathobiology links them to airway inflammation, oxidative stress, and fibrotic remodeling, with associations ranging from exacerbation of pre-existing lung conditions to asthma, hypersensitivity pneumonitis, and lung cancer. Data on human exposure remains limited to preclinical findings, and direct exposure-response relationships are poorly defined.DiscussionThis review highlights the growing burden of respiratory conditions in response to rapidly emerging environmental exposures and addresses the critical gap between this growth and existing clinical and regulatory guidelines. Standardized prospective human studies, paired with coordinated policy action, are needed to close this gap and generate effective mitigation strategies.",
  "abstract_shown": true,
  "affiliations": [
    "ivision of Pulmonary, Allergy, Sleep and Respiratory Medicine, Mayo Clinic, Jacksonville, FL, United States"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 10,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Hassan Baig"
    },
    {
      "affs": [
        0
      ],
      "name": "Deepika Karki"
    },
    {
      "affs": [
        0
      ],
      "name": "Shivanjali Santosh Gore"
    },
    {
      "affs": [
        0
      ],
      "name": "Paola Gutierrez-Gallegos"
    },
    {
      "affs": [
        0
      ],
      "name": "Regina M. Murillo-Torres"
    },
    {
      "affs": [
        0
      ],
      "name": "Tatiana A. Rojas-Zapata"
    },
    {
      "affs": [
        0
      ],
      "name": "Alejandra Yu Lee-Mateus"
    },
    {
      "affs": [
        0
      ],
      "name": "Abubakr Bajwa"
    },
    {
      "affs": [
        0
      ],
      "name": "Scott Helgeson"
    },
    {
      "affs": [
        0
      ],
      "name": "Augustine Lee"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/199bmfmaw6n7c.bib",
  "cited_by": 0,
  "doi": "10.3389/fenvh.2026.1964110",
  "fulltext_url": "https://www.frontiersin.org/articles/10.3389/fenvh.2026.1964110/full",
  "id": "199bmfmaw6n7c",
  "issns": [
    "2813-558X"
  ],
  "landing_url": "https://doi.org/10.3389/fenvh.2026.1964110",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
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      "lcc",
      "GE1-350"
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      "openalex",
      "2307|Air Quality and Health Impacts"
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  "openalex": "W7223260393",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-23",
  "publisher": "Frontiers Media S.A.",
  "ris": "https://research.draconitic.com/paper/199bmfmaw6n7c.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:57Z",
      "native_id": "991fe38eca0a459fb7b4d04f75d5bbbd",
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      "url": "https://doi.org/10.3389/fenvh.2026.1964110"
    }
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2307|Air Quality and Health Impacts",
      "subfield": "pharmacology-toxicology"
    }
  ],
  "title": "Emerging environmental exposures and pulmonary diseases",
  "title_text": "Emerging environmental exposures and pulmonary diseases",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:57Z",
  "url": "https://research.draconitic.com/paper/199bmfmaw6n7c",
  "venue": "Frontiers in Environmental Health",
  "versions": []
}