{
  "abstract": "Background: We examined temporal trends in deaths mentioning both pancreatic cancer and renal failure in the United States. Methods: We analyzed CDC WONDER multiple-cause-of-death data for adults aged ≥25 years from 1999 to 2024. Age-adjusted mortality rates (AAMRs) were assessed using Joinpoint regression. Secondary analyses quantified renal-failure co-recording among pancreatic-cancer-involving deaths, renal-failure subtypes, disparities, and comparisons with lung and bronchus, colorectal, and liver and intrahepatic bile duct cancers. Results: Overall, 31,497 deaths mentioned both conditions. The AAMR increased from 0.37 per 100,000 in 1999 to 0.82 in 2024, with the most rapid increase during 2018–2024 (annual percentage change, 10.77%; 95% CI, 7.18–18.22%). Renal failure was co-recorded in 2.98% of pancreatic-cancer-involving deaths. Corresponding proportions were 2.37% for lung and bronchus, 4.75% for colorectal, and 5.77% for liver and intrahepatic bile duct cancer; recent trends did not differ significantly from pancreatic cancer. Acute kidney failure was the most frequently recorded renal subtype (43.22%). In 2024, AAMRs were higher among males and highest among non-Hispanic Black individuals. Conclusions: Renal-failure co-recording with pancreatic cancer increased markedly after 2018 but was not unique to pancreatic cancer. Death-certificate data do not establish temporal sequence or causality; linked clinical data are needed to clarify potentially modifiable kidney-related pathways.",
  "abstract_shown": true,
  "affiliations": [
    "Academic Unit of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S5 7AU, UK",
    "Department of General Medicine, CMH Multan Institute of Medical Sciences, Multan 6000, Pakistan",
    "Department of General Medicine, Barasat Government Medical College and Hospital, Barasat 700124, India",
    "Department of Hospital Medicine, Yale New Haven Hospital, New Haven, CT 06510, USA",
    "Division of Gastroenterology, Hepatology & Motility, The University of Kansas School of Medicine, Kansas City, KS 66160, USA",
    "School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India",
    "School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Arkadeep Dhali"
    },
    {
      "affs": [
        1
      ],
      "name": "Ali Shan Hafeez"
    },
    {
      "affs": [
        2
      ],
      "name": "Jyotirmoy Biswas"
    },
    {
      "affs": [
        3
      ],
      "name": "Ashish Sharma"
    },
    {
      "affs": [
        4
      ],
      "name": "Dushyant Singh Dahiya"
    },
    {
      "affs": [
        5
      ],
      "name": "Rick Maity"
    },
    {
      "affs": [
        6
      ],
      "name": "Saikat Mandal"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1a30d892z8wem.bib",
  "cited_by": 0,
  "doi": "10.3390/epidemiologia7050124",
  "fulltext_url": "https://www.mdpi.com/2673-3986/7/5/124",
  "id": "1a30d892z8wem",
  "issns": [
    "2673-3986"
  ],
  "landing_url": "https://doi.org/10.3390/epidemiologia7050124",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RC31-1245"
    ],
    [
      "openalex",
      "2730|Pancreatic and Hepatic Oncology Research"
    ]
  ],
  "openalex": "W7208792330",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-01",
  "publisher": "MDPI AG",
  "ris": "https://research.draconitic.com/paper/1a30d892z8wem.ris",
  "sources": [
    {
      "first_seen": "2026-10-31T14:21:27Z",
      "native_id": "046eb2d45b424beeae718b1b8f922eae",
      "source": "doaj",
      "url": "https://doi.org/10.3390/epidemiologia7050124"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2730|Pancreatic and Hepatic Oncology Research",
      "subfield": "oncology"
    }
  ],
  "title": "Deaths Mentioning Both Pancreatic Cancer and Renal Failure in the United States, 1999–2024: Temporal Trends and Disparities",
  "title_text": "Deaths Mentioning Both Pancreatic Cancer and Renal Failure in the United States, 1999–2024: Temporal Trends and Disparities",
  "type": "peer-reviewed",
  "updated_at": "2026-10-31T14:21:27Z",
  "url": "https://research.draconitic.com/paper/1a30d892z8wem",
  "venue": "Epidemiologia",
  "versions": []
}