{
  "abstract": "Background: Perioperative health education is essential for patients undergoing gastrointestinal surgery, but conventional approaches are often limited by time, workload, continuity, and personalization. Artificial intelligence (AI) may offer a more accessible and interactive approach to patient education. This trial aims to evaluate whether a WeChat-based, expert knowledge-constrained AI health education system can improve anxiety and other patient-reported outcomes in patients undergoing gastrointestinal surgery.\n\nMethods: This is a single-center, open-label, parallel-group randomized controlled trial with a 1:1 allocation ratio. A total of 120 eligible patients will be recruited from the Department of Gastrointestinal Surgery at Chengdu Third People’s Hospital and randomly assigned to either an intervention group or a control group. The control group will receive usual perioperative care and conventional health education, while the intervention group will additionally receive a WeChat-based AI-supported health education intervention for 3 months. The primary outcome is anxiety measured by the Hospital Anxiety and Depression Scale-Anxiety subscale. Secondary outcomes include depression, perceived social support, self-efficacy, health-related quality of life, and eHealth literacy. Outcomes will be assessed at baseline, discharge, 3 months, and 6 months. Analyses will primarily follow the intention-to-treat principle.\n\nEthics and dissemination: This study is a low-risk behavioral intervention trial. Study findings will be disseminated through peer-reviewed publications and other academic channels. Ethical approval for the study was obtained from the Medical Ethics Committee of Chengdu Third People’s Hospital (Ethics No: 2026-S-69). The clinical trial is registered under ChiCTR2600122411, with registration completed on April 2026.\n\nClinical trial registration: https://www.chictr.org.cn/ , identifier ChiCTR2600122411.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Medical Affairs, The Third People's Hospital of Chengdu , ,",
    "Department of Nursing, The Fourth People's Hospital of Chengdu , ,",
    "Department of Medical Affairs, Chengdu Women's and Children's Central Hospital , ,",
    "Department of Quality Evaluation and Medical Record Management, The Third People's Hospital of Chengdu , ,",
    "Department of Gastroenterology, The Fourth People's Hospital of Zigong , ,",
    "School of Education, Chengdu College of Arts and Sciences , ,",
    "Hospital Administration Office, The Third People's Hospital of Chengdu , ,"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 8,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Li Liu"
    },
    {
      "affs": [
        1
      ],
      "name": "Xu Du"
    },
    {
      "affs": [
        2
      ],
      "name": "Guangli Yang"
    },
    {
      "affs": [
        3
      ],
      "name": "Shuyao Xiang"
    },
    {
      "affs": [
        0
      ],
      "name": "Hua Guo"
    },
    {
      "affs": [
        4
      ],
      "name": "Lu Huang"
    },
    {
      "affs": [
        5
      ],
      "name": "Yun-Hua Li"
    },
    {
      "affs": [
        6
      ],
      "name": "Hongtao Yu"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1axwzx0w62srm.bib",
  "cited_by": 0,
  "doi": "10.3389/fpubh.2026.1862627",
  "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661914/?tool=EBI",
  "id": "1axwzx0w62srm",
  "issns": [
    "2296-2565"
  ],
  "landing_url": "https://europepmc.org/article/PMC/PMC13661914",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "3600|Mobile Health and mHealth Applications"
    ]
  ],
  "openalex": "W7214970252",
  "pdf_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661914/pdf/?tool=EBI",
  "pmcid": "PMC13661914",
  "pmid": null,
  "published": "2026-09-30",
  "publisher": "Frontiers Media SA",
  "ris": "https://research.draconitic.com/paper/1axwzx0w62srm.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:20Z",
      "native_id": "PMC:PMC13661914",
      "source": "europepmc",
      "url": "https://europepmc.org/article/PMC/PMC13661914"
    },
    {
      "first_seen": "2026-10-30T12:20:22Z",
      "native_id": "10.3389/fpubh.2026.1862627",
      "source": "crossref",
      "url": "https://www.frontiersin.org/articles/10.3389/fpubh.2026.1862627/full"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "issn:2296-2565",
      "subfield": "epidemiology-public-health"
    }
  ],
  "title": "A WeChat-based, expert knowledge-constrained artificial intelligence health education intervention for patients undergoing gastrointestinal surgery: protocol for a randomized controlled trial",
  "title_text": "A WeChat-based, expert knowledge-constrained artificial intelligence health education intervention for patients undergoing gastrointestinal surgery: protocol for a randomized controlled trial",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:22Z",
  "url": "https://research.draconitic.com/paper/1axwzx0w62srm",
  "venue": "Frontiers in public health",
  "versions": []
}