{
  "abstract": "AI agents now run sequencing pipelines, but their outputs are checked by proxy, with rubrics or language-model judges. LongVerse turns one English sentence into haplotype-resolved DNA methylation from Nanopore or PacBio reads, through agents that read the data, supply arguments to a pinned pipeline and never write code. On HG002, a healthy reference genome, agent and human expert produced byte-identical calls (r = 1.000) that agreed with bisulfite sequencing (r = 0.943, 0.884), at $0.12 to $0.54 of conversation per run. A consensus agent that admits any per-site caller reduced error 10.7 percent against the best published caller.",
  "abstract_shown": true,
  "affiliations": [
    "University of Southern California"
  ],
  "article_type": "New results",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "name": "Y. Liu"
    },
    {
      "name": "Q. Zhang"
    },
    {
      "affs": [
        0
      ],
      "name": "S. Li"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1c58zdcb1g1fk.bib",
  "cited_by": 0,
  "doi": "10.64898/2026.10.13.758965",
  "fulltext_url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758965v1.full",
  "id": "1c58zdcb1g1fk",
  "issns": [],
  "landing_url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758965v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "biorxiv",
      "bioinformatics"
    ],
    [
      "openalex",
      "1312|Epigenetics and DNA Methylation"
    ]
  ],
  "openalex": "W7223060573",
  "pdf_url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758965v1.full.pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-13",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1c58zdcb1g1fk.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:28:38Z",
      "native_id": "10.64898/2026.10.13.758965",
      "source": "biorxiv",
      "url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758965v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "biorxiv:bioinformatics",
      "subfield": "bioinformatics"
    }
  ],
  "title": "LongVerse: verified AI agents for Nanopore and PacBio DNA methylation analysis",
  "title_text": "LongVerse: verified AI agents for Nanopore and PacBio DNA methylation analysis",
  "type": "preprint",
  "updated_at": "2026-10-30T12:28:38Z",
  "url": "https://research.draconitic.com/paper/1c58zdcb1g1fk",
  "venue": "bioRxiv",
  "versions": []
}