{ "abstract": "Objective: To assess the current surgical site infection prevention practices in neonatal surgery, especially focusing on the factors that determine the duration of perioperative antibiotic prophylaxis (PAP) and the differences between pediatric surgeons and neonatologists.\n\nStudy design: We performed a questionnaire survey, which targeted neonatologists, pediatric surgeons, and infectious disease specialists at pediatric hospitals or university hospitals in Japan.\n\nResults: Responses were obtained from 32 hospitals. Some practices, such as criteria for discontinuing PAP, intraoperative re-administration of PAP, and preoperative decontamination of methicillin-resistant Staphylococcus aureus, were different between neonatologists and pediatric surgeons. Regarding criteria for discontinuing PAP, pediatric surgeons tended to select “fixed duration”, while neonatologists more often relied on “C-reactive protein levels.”\n\nConclusion: PAP discontinuation practices in neonatal surgery reflect distinct time-based and biomarker-guided decision-making approaches between pediatric surgeons and neonatologists, indicating the need for clearer evidence and consensus. More standardized, evidence-based approaches are required.", "abstract_shown": true, "affiliations": [ "Department of Pediatric Surgery, The University of Tokyo Hospital, Tokyo, Japan", "Department of Pediatric Infectious Diseases, Hokkaido Medical Center for Child Health and Rehabilitation, Sapporo, Japan", "Department of Rheumatics and Infectious Disease, Miyagi Children’s Hospital, Miyagi, Japan", "Department of Infectious Diseases, Gunma Children’s Medical Center, Shibukawa, Japan", "Department of Pediatric Infectious Diseases, Ibaraki Children’s Hospital, Mito, Japan", "Division of Infectious Diseases, Chiba Children’s Hospital, Chiba, Japan", "Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan", "Infection and Immunology, Kanagawa Children’s Medical Center, Yokohama, Japan", "Department of Infectious Diseases, Nagano Children’s Hospital, Azumino, Japan", "Division of Pediatric Infectious Diseases, Shizuoka Children’s Hospital, Shizuoka, Japan", "Department of General Pediatrics, Aichi Children’s Health and Medical Center, Aichi, Japan", "Department of Perinatal and Pediatric Infectious Diseases, Osaka Women’s and Children’s Hospital, Izumi, Osaka, Japan", "Division of Infectious Diseases, Department of Pediatrics, Hyogo Prefectural Kobe Children’s Hospital, Hyogo, Japan", "Department of Pediatrics, Shikoku Medical Center for Children and Adults, Kagawa, Japan", "General Medical Department, Fukuoka Children’s Hospital, Fukuoka, Japan", "Department of Pediatrics, Division of Pediatric Infectious Diseases, Okinawa Prefectural Nanbu Medical Center & Children’s Medical Center, Okinawa, Japan", "Center for Perinatal and Neonatal Medicine, Tohoku University Hospital, Miyagi, Japan", "Department of Pediatrics, School of Medicine, Fukushima Medical University, Fukushima, Japan", "Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan", "Department of Hepato-Biliary-Pancreatic Surgery and Pediatric Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan", "Department of Pediatric Surgery, Saitama Medical University Hospital, Saitama, Japan", "Department of Infection Control and Prevention, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan", "Department of Pediatric General and Urogenital Surgery, Juntendo University Graduate School of Medicine, Tokyo, Japan", "Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan", "Department of Pediatrics, St Marianna University School of Medicine, Kanagawa, Japan", "Department of Pediatrics, Chiba University Hospital, Chiba, Japan", "Department of Infectious Diseases, Nagoya University Hospital, Aichi, Japan", "Department of Pediatrics, Fujita health University School of Medicine, Toyoake, Japan", "Department of Infectious Diseases, University of Osaka Hospital, Osaka, Japan", "Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan", "Department of Pediatrics, Kyushu University, Fukuoka, Japan", "Department of Pediatrics, Kagoshima University Hospital, Kagoshima, Japan", "Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan" ], "article_type": "research article", "arxiv": null, "author_total": 34, "authors": [ { "affs": [ 0 ], "name": "Tomohiro Sunouchi", "orcid": "0000-0002-4776-8880" }, { "affs": [ 0 ], "name": "Jun Fujishiro", "orcid": "0000-0001-9451-8318" }, { "affs": [ 1 ], "name": "Toru Higuchi" }, { "affs": [ 2 ], "name": "Hiroki Sakurai" }, { "affs": [ 3 ], "name": "Akihiko Shimizu" }, { "affs": [ 4 ], "name": "Sho Ishii" }, { "affs": [ 5 ], "name": "Taizo Kusano" }, { "affs": [ 6 ], "name": "Yuho Horikoshi" }, { "affs": [ 7 ], "name": "Yoshiaki Shikama" }, { "affs": [ 8 ], "name": "Takemi Murai" }, { "affs": [ 9 ], "name": "Takayo Shoji" }, { "affs": [ 10 ], "name": "Kenta Ito" }, { "affs": [ 11 ], "name": "Masatoshi Nozaki", "orcid": "0000-0003-0391-6957" }, { "affs": [ 12 ], "name": "Shinsuke Mizuno" }, { "affs": [ 13 ], "name": "Takafumi Okada" }, { "affs": [ 14 ], "name": "Takayuki Hoshina" }, { "affs": [ 15 ], "name": "Yoshiaki Cho" }, { "affs": [ 16 ], "name": "Yoshie Sakurai" }, { "affs": [ 17 ], "name": "Hisao Okabe" }, { "affs": [ 18 ], "name": "Daisuke Tamura" }, { "affs": [ 19 ], "name": "Yuki Muta" }, { "affs": [ 20 ], "name": "Chizuka Seki" }, { "affs": [ 21 ], "name": "Ryu Yoneda" }, { "affs": [ 22 ], "name": "Naho Fujiwara" }, { "affs": [ 23 ], "name": "Masayoshi Shinjoh" }, { "affs": [ 24 ], "name": "Tomohiro Katsuta" }, { "affs": [ 25 ], "name": "Koo Nagasawa" }, { "affs": [ 26 ], "name": "Toshihiko Okumura" }, { "affs": [ 27 ], "name": "Hiroki Miura" }, { "affs": [ 28 ], "name": "Yoshiki Kusama", "orcid": "0000-0002-7072-2338" }, { "affs": [ 29 ], "name": "Kazumichi Fujioka", "orcid": "0000-0002-9913-6447" }, { "affs": [ 30 ], "name": "Yoshitomo Motomura" }, { "affs": [ 31 ], "name": "Yoshihiro Takahashi" }, { "affs": [ 32 ], "name": "Chikara Ogimi", "orcid": "0000-0002-2166-8152" } ], "bibtex": "https://research.draconitic.com/paper/1eaecghd1vkqn.bib", "cited_by": 0, "doi": "10.1038/s41372-026-02803-w", "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13731140/", "id": "1eaecghd1vkqn", "issns": [ "0743-8346", "1476-5543" ], "landing_url": "https://doi.org/10.1038/s41372-026-02803-w", "language": "en", "licence": "CC-BY-NC-ND-4.0", "licence_label": "CC BY-NC-ND 4.0", "licence_source": "article", "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/", "metadata_licence": null, "native_subjects": [ [ "heading", "Article" ], [ "openalex", "2746|Surgical site infection prevention" ] ], "openalex": "W7171803007", "pdf_url": "https://www.nature.com/articles/s41372-026-02803-w.pdf", "pmcid": "PMC13731140", "pmid": "42533059", "published": "2026-07-30", "publisher": null, "ris": "https://research.draconitic.com/paper/1eaecghd1vkqn.ris", "sources": [ { "first_seen": "2026-11-08T12:21:23Z", "native_id": "PMC13731140", "source": "pmc", "url": "https://doi.org/10.1038/s41372-026-02803-w" } ], "subjects": [ { "field": "medicine", "origin": "openalex:2746|Surgical site infection prevention", "subfield": "surgery" } ], "title": "Differences in practices for surgical site infection prevention in neonatal surgery between neonatologists and pediatric surgeons: a multicenter survey in Japan", "title_text": "Differences in practices for surgical site infection prevention in neonatal surgery between neonatologists and pediatric surgeons: a multicenter survey in Japan", "type": "peer-reviewed", "updated_at": "2026-11-08T12:21:23Z", "url": "https://research.draconitic.com/paper/1eaecghd1vkqn", "venue": "Journal of Perinatology", "versions": [] }