{
  "abstract": "Introduction: Sedentary behaviour increases during cancer treatment, often because of side effects from treatment. However, evidence on interventions specifically targeting sedentary behaviour during active cancer treatment is limited. Therefore, the aims of the reduce sedentary behaviour during cancer treatment (RedSedCan) study are to investigate the effects of sedentary behaviour on health outcomes and to explore the economic, environmental and social sustainability perspectives of a digital support intervention for reducing sedentary behaviour in individuals with breast, prostate or colorectal cancer receiving neoadjuvant or adjuvant cancer treatment. In addition, participants’ experiences with the intervention as well as healthcare professionals’ perspectives for supporting individuals with cancer to reduce sedentary behaviour will be explored.\n\nMethods and analysis: A multicentre randomised controlled trial will be conducted with short-term (3 months) and long-term (6, 12 and 24 months) follow-up. After baseline assessments, participants will be randomised into one of two groups as follows: a digital support intervention group or a control group receiving usual care. The digital support intervention—the RedSedCan intervention—consists of access to a home page containing information and tips about how to reduce sedentary behaviour, a commercially available step-counting mobile application, use of mobile phone reminder/alarm functions and four digital meetings with physiotherapists. During these meetings, participants will receive support for setting and reviewing goals. The main outcome is time spent engaging in sedentary behaviour, which is measured with a thigh-worn accelerometer at 3 months. Secondary outcomes include long-term follow-ups, physical activity, health-related outcomes, health economic effects and greenhouse gas emissions from interventions and healthcare. In addition, the experiences of participants undergoing the intervention and the attitudes and perceived barriers and facilitating factors of healthcare professionals for supporting individuals with cancer to reduce sedentary behaviour will be explored qualitatively.\n\nEthics and dissemination: Ethical approval has been obtained from the appropriate ethics review authority. Findings will be disseminated through peer-reviewed publications, conference presentations and other relevant scientific and patient communities.\n\nTrial registration number: NCT06719206.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Health Sciences, Innovation and Design, Mälardalen University, Västerås, Sweden",
    "Centre for Welfare Change, Department of Health Sciences, Innovation and Design, Mälardalen University, Västerås, Sweden",
    "Department of Women’s and Children’s Health, Uppsala university, Uppsala, Sweden"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Lisa Rådman"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Johanna Zetterlund"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Petra von Heideken Wågert",
      "orcid": "0000-0001-6292-7010"
    },
    {
      "affs": [
        0,
        2
      ],
      "name": "Anna Henriksson",
      "orcid": "0000-0002-2631-7757"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1extemh4nb08f.bib",
  "cited_by": 0,
  "doi": "10.1136/bmjopen-2026-125120",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13723854/",
  "id": "1extemh4nb08f",
  "issns": [
    "2044-6055",
    "2044-6055"
  ],
  "landing_url": "https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-125120",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "1506"
    ],
    [
      "heading",
      "1717"
    ],
    [
      "heading",
      "Oncology"
    ],
    [
      "heading",
      "Protocol"
    ]
  ],
  "openalex": null,
  "pdf_url": null,
  "pmcid": "PMC13723854",
  "pmid": "42957304",
  "published": "2026-10-29",
  "publisher": "BMJ",
  "ris": "https://research.draconitic.com/paper/1extemh4nb08f.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:44Z",
      "native_id": "10.1136/bmjopen-2026-125120",
      "source": "crossref",
      "url": "https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-125120"
    },
    {
      "first_seen": "2026-11-04T12:22:25Z",
      "native_id": "PMC13723854",
      "source": "pmc",
      "url": "https://doi.org/10.1136/bmjopen-2026-125120"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "heading:Oncology",
      "subfield": "oncology"
    }
  ],
  "title": "Does a digital support intervention reduce sedentary behaviour during cancer treatment in individuals with breast, prostate or colorectal cancer? Study protocol for a Swedish multicentre randomised controlled trial",
  "title_text": "Does a digital support intervention reduce sedentary behaviour during cancer treatment in individuals with breast, prostate or colorectal cancer? Study protocol for a Swedish multicentre randomised controlled trial",
  "type": "peer-reviewed",
  "updated_at": "2026-11-04T12:22:25Z",
  "url": "https://research.draconitic.com/paper/1extemh4nb08f",
  "venue": "BMJ Open",
  "versions": []
}