{
  "abstract": "Background\n\nAortic vascular graft and endograft infections (aortic VGEI) remain a rare but life-threatening complication following aortic reconstruction. This retrospective study compares outcomes between bovine pericardial graft prostheses and rifampicin-soaked Dacron grafts.Methods\n\nIn this retrospective single-center cohort study, we analyzed 62 patients between January 2018 and December 2025 for aortic vascular graft or endograft infection requiring graft explantation and in-situ reconstruction. Patients received either a bovine pericardial graft (n=21) or a rifampicin-soaked Dacron prosthesis (n=41). Survival, treatment failure, perioperative variables, and microbiology were analyzed.Results\n\nPatients in the bovine and rifampicin groups were comparable in terms of age (72.57 vs. 73.58 years, p = 0.685) and sex distribution (85.71% vs. 73.17% male, p = 0.346). BMI, preoperative dialysis, and aortic clamping time were higher in the bovine group. Four treatment failures, defined as persistent or recurrent infection of the reconstructed aortic segment, occurred during follow-up; all were observed after reconstruction with rifampicin-soaked Dacron (4/41, 9.8%), whereas no treatment failure occurred in the bovine pericardial group (0/21). In-hospital mortality was comparable between groups (n=3:14.3% vs. n=8: 19.5%, p = 0.735). Kaplan-Meier analysis demonstrated no significant difference in survival (p = 0.256) or treatment failure rate (p = 0.833). Candida spp. were the most frequent pathogens (27.8%) and significantly associated with secondary aorto-enteric fistula (p=0.003).Conclusion\n\nSurvival and treatment failure rates were comparable, with a trend toward fewer infection-related complications after bovine pericardial grafting. Despite use in more complex cases, bovine grafts may represent a promising biological alternative.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Vascular and Endovascular Surgery, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. viktoriaweronika.strzoda@ukmuenster.de.",
    "Department of Vascular and Endovascular Surgery, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Viktoria Weronika Strzoda"
    },
    {
      "affs": [
        1
      ],
      "name": "Miroslav Dimitrov Yordanov"
    },
    {
      "affs": [
        1
      ],
      "name": "Alexander Oberhuber"
    },
    {
      "affs": [
        1
      ],
      "name": "Abdulhakim Ibrahim"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1fa4g4sj65a0w.bib",
  "cited_by": 0,
  "doi": "10.1007/s00423-026-04349-z",
  "fulltext_url": "https://europepmc.org/articles/PMC13695657",
  "id": "1fa4g4sj65a0w",
  "issns": [
    "1435-2443",
    "1435-2451"
  ],
  "landing_url": "https://europepmc.org/article/MED/42925319",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2746|Infectious Aortic and Vascular Conditions"
    ]
  ],
  "openalex": "W7223319094",
  "pdf_url": "https://europepmc.org/articles/PMC13695657?pdf=render",
  "pmcid": "PMC13695657",
  "pmid": "42925319",
  "published": "2026-10-23",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1fa4g4sj65a0w.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:20:33Z",
      "native_id": "MED:42925319",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42925319"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Infectious Aortic and Vascular Conditions",
      "subfield": "surgery"
    }
  ],
  "title": "Rifampicin-soaked versus bovine prostheses in the management of aortic graft infections: a retrospective single-center cohort study.",
  "title_text": "Rifampicin-soaked versus bovine prostheses in the management of aortic graft infections: a retrospective single-center cohort study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:20:33Z",
  "url": "https://research.draconitic.com/paper/1fa4g4sj65a0w",
  "venue": "Langenbeck's archives of surgery",
  "versions": []
}