{
  "abstract": "iCanCope™ (ICC) is a digital self-management program for 15-25 year olds with chronic pain. This study evaluated program satisfaction and efficacy through a two arm randomized controlled trial in Canadian tertiary care pain clinics. Participants were randomized to receive either ICC (app and website with symptom tracking and trending, pain education, goal setting, library, community forum) or an identically branded active control program with limited features. Outcomes were assessed at baseline, postprogram (2 months; T2), and follow-up (6 months; T3). Satisfaction was assessed using the Acceptability eScale and qualitatively with a subset of intervention participants. Linear mixed effects models characterized treatment effects on primary (pain interference) and secondary outcomes. Of 302 enrolled participants, 297 were analyzed (mean age = 17.1 ± 2.4, 83% female). Outcome completion rates were 89% at T2 and 71% at T3. Program acceptability was high in both the intervention (33.9 ± 7.0) and control group (32.7 ± 6.8). Most participants exhibited moderate to high engagement with daily checkins (intervention: 79%, active control: 80%). No significant treatment effects were found. However, improvements across time in pain interference at T2 (β = -0.58, p < .001) and T3 (β = -0.64, p = .0016) and improvements in knowledge about managing pain at T2 (β = -0.54, p < .0001) and T3 (β = -1.04, p < .0001) were found for both groups. Most (15/16) interviewees reported that ICC enhanced their confidence and/or ability to engage in pain self-management. Digitally mediated symptom tracking and trending and pain education is engaging and beneficial for 15-25 year olds with chronic pain. Use of an active-control may have diminished the ability to detect treatment-group effects. ICC has been translated to French-Canadian and publicly released as a free self-management tool. Trial Registration: ClinicalTrials.gov, NCT02601755.",
  "abstract_shown": true,
  "affiliations": [
    "The Hospital for Sick Children, Child Health Evaluative Sciences, Toronto, ON, Canada.",
    "Institute of Health Policy, Management & Evaluation, University of Toronto, Toronto, ON, Canada.",
    "Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, Washington, USA.",
    "Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.",
    "Departments of Family Medicine and Anesthesiology, Peri-operative and Pain Medicine, University of Calgary, Calgary, Alberta, Canada.",
    "Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, Ontario, Canada.",
    "Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.",
    "Centre for Pediatric Pain Research, IWK Health, Halifax, Nova Scotia, Canada.",
    "Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, Canada.",
    "Toronto Academic Pain Medicine Institute, Women's College Hospital, Toronto, Ontario, Canada.",
    "Department of Anesthesia, Pain Management & Perioperative Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.",
    "Alberta Children's Hospital, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.",
    "Department of Anesthesiology & Pain Medicine, University of Ottawa, Ottawa, ON, Canada.",
    "Department of Psychology, The Ottawa Hospital, Ottawa, ON, Canada.",
    "Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.",
    "Michael G. DeGroote Pain Clinic, Hamilton Health Sciences, Hamilton, Ontario, Canada.",
    "School of Nursing, McMaster University, Hamilton, Ontario, Canada.",
    "Center for Digital Therapeutics, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.",
    "Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 24,
  "authors": [
    {
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        0,
        1
      ],
      "name": "Chitra Lalloo",
      "orcid": "0000-0003-2794-7061"
    },
    {
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        0
      ],
      "name": "Fareha Nishat"
    },
    {
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        2,
        3
      ],
      "name": "Tonya Palermo"
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    {
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        4
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      "name": "Lori Montgomery"
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    {
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        5
      ],
      "name": "Fiona Campbell"
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    {
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        6
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      "name": "Krista Baerg",
      "orcid": "0000-0001-5192-7285"
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    {
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        7
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      "name": "Jill Chorney"
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    {
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        8
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      "name": "Bruce Dick"
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    {
      "affs": [
        9
      ],
      "name": "Tania Di Renna"
    },
    {
      "affs": [
        10
      ],
      "name": "Karim Mukhida"
    },
    {
      "affs": [
        11
      ],
      "name": "Melanie Noel"
    },
    {
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        12,
        13,
        14
      ],
      "name": "Patricia Poulin"
    },
    {
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        8
      ],
      "name": "Mark Simmonds"
    },
    {
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        15
      ],
      "name": "Ramesh Zacharias"
    },
    {
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        0
      ],
      "name": "Lauren Harris"
    },
    {
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        0
      ],
      "name": "Cleo Davies-Chalmers"
    },
    {
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        16
      ],
      "name": "Carley Ouellette"
    },
    {
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        1
      ],
      "name": "Vina Mohabir"
    },
    {
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        17
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      "name": "Quynh Pham"
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    {
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        17
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      "name": "Joe Cafazzo"
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    {
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        18
      ],
      "name": "Sarah Brennenstuhl"
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    {
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      ],
      "name": "Brenna McDermott"
    },
    {
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        0
      ],
      "name": "Rachel Kelly"
    },
    {
      "affs": [
        0,
        18
      ],
      "name": "Jennifer N Stinson",
      "orcid": "0000-0002-9969-8052"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1gddqbyhdggnb.bib",
  "cited_by": 0,
  "doi": "10.1080/24740527.2026.2717605",
  "fulltext_url": "https://europepmc.org/articles/PMC13679339",
  "id": "1gddqbyhdggnb",
  "issns": [
    "2474-0527"
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  "landing_url": "https://europepmc.org/article/MED/42899170",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "2735|Pediatric Pain Management Techniques"
    ]
  ],
  "openalex": "W7222032199",
  "pdf_url": "https://europepmc.org/articles/PMC13679339?pdf=render",
  "pmcid": "PMC13679339",
  "pmid": "42899170",
  "published": "2026-10-15",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1gddqbyhdggnb.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:33Z",
      "native_id": "MED:42899170",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42899170"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2735|Pediatric Pain Management Techniques",
      "subfield": "reproductive-child"
    }
  ],
  "title": "Impacts of the iCanCope Digital Pain Self-Management Program Among Adolescents and Young Adults With Chronic Pain: A Randomized Controlled Trial.",
  "title_text": "Impacts of the iCanCope Digital Pain Self-Management Program Among Adolescents and Young Adults With Chronic Pain: A Randomized Controlled Trial.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:33Z",
  "url": "https://research.draconitic.com/paper/1gddqbyhdggnb",
  "venue": "Canadian journal of pain = Revue canadienne de la douleur",
  "versions": []
}