{
  "abstract": "Cissus microdonta Planch. is traditionally used to treat jaundice in Madagascar. This study aimed to investigate the phytochemical profile of Cissus microdonta stems and evaluate its antioxidant activity. Hexane (1.75%), ethyl acetate (3.74%), and ethanol (1.67%) extracts of the plant stems were obtained by maceration. Phytochemical screening was performed. The antioxidant activity of the plant was evaluated using the DPPH assay. Compounds from the active extracts were isolated using liquid chromatography on silica gel and identified via spectroscopic analysis. The presence of alkaloids, leucoanthocyanins, saponins, triterpenes, saturated sterols, and leucoanthocyanidins was established. The evaluation of the antioxidant activity of the ethanolic extract of the plant revealed significant free-radical-scavenging capacity. One compound was isolated from the active ethyl acetate extract and identified as ursolic acid. This research has enhanced the understanding of the phytochemical profile and biological properties of Cissus microdonta Planch., suggesting that the plant may be a potential source of natural antioxidants.",
  "abstract_shown": true,
  "affiliations": [
    "Mention Physique-chimie",
    "University of Toamasina",
    "Laboratoire de Chimie des Substances Naturelles et Chimie Organique Biologique (LCSN/COB",
    "University of Antananarivo"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 5,
  "authors": [
    {
      "affs": [
        0,
        1
      ],
      "name": "Séraphine Kanto Aricia OLIARISOA"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Fanamperantsoa Andrianina RAMANAMIHAJA",
      "orcid": "0009-0006-4200-7835"
    },
    {
      "affs": [
        0,
        1,
        2,
        3
      ],
      "name": "Faramalala Louise RABEMANDROSO"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Stanislas Fulgence LAHADSON"
    },
    {
      "affs": [
        2,
        3
      ],
      "name": "Herilala Léa RASOANAIVO"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1gpvx0z2vnbvz.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15010107/v1",
  "fulltext_url": null,
  "id": "1gpvx0z2vnbvz",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010107/v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1110|Medicinal Plant Research"
    ]
  ],
  "openalex": "W7221036637",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15010107/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-10-08",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/1gpvx0z2vnbvz.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:22Z",
      "native_id": "10.26434/chemrxiv.15010107",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15010107/v1"
    }
  ],
  "subjects": [
    {
      "field": "biology",
      "origin": "openalex:1110|Medicinal Plant Research",
      "subfield": "plant-biology"
    }
  ],
  "title": "Phytochemical Analysis and evaluation of the Antioxidant Activity of Cissus microdonta Planch.",
  "title_text": "Phytochemical Analysis and evaluation of the Antioxidant Activity of Cissus microdonta Planch.",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:22Z",
  "url": "https://research.draconitic.com/paper/1gpvx0z2vnbvz",
  "venue": "ChemRxiv",
  "versions": []
}