{
  "abstract": "Globally, especially in the Asia Pacific region, chronic hepatitis B infection has led to an undesirable escalating morbidity and mortality with acute-on chronic liver failure, end-staged liver cirrhosis, and hepatocellular carcinoma. This has happened despite the past four decades of major scientific advances made in screening methods, vaccination strategies, highly effective low-cost anti-viral therapies, and surveillance strategies for early detection of hepatocellular carcinoma. To address this health threat, APASL has formed a Viral Elimination Taskforce to unite key opinion leaders from its member countries and regions. The ongoing shifts in hepatitis B epidemiology, socioeconomic changes, and advancements in technology are taken into consideration. With the conjoint efforts of all the members of the APASL Viral Elimination Taskforce, these clinical practice guidelines have been formulated aiming to facilitate healthcare professionals, policy-makers, and patients in making practical and cost-effective management decisions for chronic hepatitis B infection. Altogether, it provides recommendations in 13 major areas related to screening, vaccination, treatment, and HCC surveillance. The implementation of these clinical practice guidelines represents major APASL effort toward elimination of the disease burden due to chronic hepatitis B infection in Asia Pacific region.",
  "abstract_shown": true,
  "affiliations": [
    "Beijing Friendship Hospital, Capital Medical University, Beijing, China",
    "Institute of Liver and Biliary Sciences, New Delhi, India",
    "JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China",
    "Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, South Korea",
    "Liver Transplantation Center, Bahçeşehir University, Istanbul, Turkey",
    "Department of Infectious Diseases, Shengjing Hospital of China Medical University, Shenyang, China",
    "Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt",
    "Center for Fatty Liver, Department of Gastroenterology, Shanghai Key Lab of Pediatric Gastroenterology and Nutrition, Xin Hua Hospital, Shanghai Jiao Tong University, Shanghai, China",
    "Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia",
    "Hepatic Hospital, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China",
    "Storr Liver Centre, The Westmead Millennium Institute for Medical Research, Westmead Hospital, The University of Sydney, Sydney, Australia",
    "Yerevan Medical Scientific Center, Yerevan, Armenia",
    "Department of Gastroenterology & Hepatology, Singapore General Hospital, Singapore, Singapore",
    "Aga Khan University, Karachi-74800, Pakistan",
    "Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China",
    "Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan",
    "Senior Department of Hepatology, Fifth Medical Center of Chinese, PLA General Hospital, Beijing, China",
    "Division of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minamiuonuma, 949-7302, Japan",
    "National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan",
    "Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, 03080, South Korea",
    "Department of Gastroenterology & Hepatology, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty Universitas Indonesia, Jakarta, Indonesia",
    "Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia",
    "Department and Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China",
    "Istanbul Health and Technology University, Istanbul, Turkey",
    "Department of Gastroenterology and Hepatology, Okayama University, Okayama, Japan",
    "Department of Medicine, Cardinal Santos Medical Center, Mandaluyong, Philippines",
    "Partnership for Health Advancement in Vietnam, Hanoi, Vietnam",
    "Communicable Disease Control Department & Secretariat of Viral Hepatitis, Ministry of Health, Phnom Penh, Cambodia",
    "Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines",
    "Division of Gastroenterology, Faculty of Medicine Siriraj Hospital, Mahidol University, Salaya, Thailand",
    "St. Vincent's Hospital Melbourne, University of Melbourne, Melbourne, Australia",
    "Treatment and Research Center for Infectious Diseases, The Fifth Medical Center of PLA General Hospital, Beijing, 100039, China",
    "Department of Infectious Disease, Center for Liver Disease, Peking University First Hospital, Beijing, China",
    "School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, China",
    "Medical Data Analytics Centre, Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China",
    "Medical Data Analytics Centre, Department of Medicine & Therapeutics, Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China",
    "Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan",
    "Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency Response, Huashan Hospital, Fudan University, Shanghai, China",
    "Department of Microbiology and Centre for Infectious Diseases, Peking University Health Science Centre, Beijing, China",
    "The University of Hong Kong, Hong Kong SAR, China"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 49,
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      "name": "Hong You",
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      "name": "Rakhi Maiwall",
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      "name": "Jing Chen"
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      "name": "Sang Hoon Ahn",
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      "name": "Kadir Dokmeci"
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      "name": "Jinlin Hou",
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      "name": "Shang‐Chin Huang",
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      "name": "Dong Ji",
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      "name": "Jidong Jia",
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      "name": "Tatsuo Kanda",
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      "name": "Jia‐Horng Kao",
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      "name": "Yoon Jun Kim",
      "orcid": "0000-0001-9141-7773"
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      "name": "Cosmas Rinaldi A. Lesmana"
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      "name": "Rosmawati Binti Mohamed",
      "orcid": "0000-0001-7595-5045"
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        22
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      "name": "Qin Ning",
      "orcid": "0000-0002-2027-9593"
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      "affs": [
        23
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      "name": "Necati Ormeci",
      "orcid": "0000-0002-8909-2102"
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      "affs": [
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      "name": "Motoyuki Otsuka",
      "orcid": "0000-0003-2869-2881"
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      "affs": [
        25
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      "name": "Diana Payawal"
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    {
      "affs": [
        26
      ],
      "name": "Pham Thanh Thuy"
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        27
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      "name": "Keo Sailey"
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    {
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        1
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      "name": "Manoj Kumar Sharma"
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    {
      "affs": [
        28
      ],
      "name": "Jose Decena Sollano",
      "orcid": "0000-0003-3227-1983"
    },
    {
      "affs": [
        14
      ],
      "name": "Jian Sun",
      "orcid": "0000-0001-5320-227X"
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    {
      "affs": [
        29
      ],
      "name": "Tawesak Tanwandee",
      "orcid": "0000-0001-7634-0843"
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    {
      "affs": [
        30
      ],
      "name": "Alexander J. V. Thompson",
      "orcid": "0000-0001-9882-0071"
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    {
      "affs": [
        31
      ],
      "name": "Fang Wang",
      "orcid": "0000-0002-5971-2622"
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    {
      "affs": [
        32
      ],
      "name": "Guiqiang Wang",
      "orcid": "0000-0002-0317-7536"
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    {
      "affs": [
        33
      ],
      "name": "Lai Wei"
    },
    {
      "affs": [
        34
      ],
      "name": "Grace Lai‐Hung Wong",
      "orcid": "0000-0002-2863-9389"
    },
    {
      "affs": [
        34
      ],
      "name": "Vincent Wai Sun Wong",
      "orcid": "0000-0003-2215-9410"
    },
    {
      "affs": [
        2
      ],
      "name": "Eng Kiong Yeoh"
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    {
      "affs": [
        35
      ],
      "name": "Terry Cheuk‐Fung Yip",
      "orcid": "0000-0002-1819-2464"
    },
    {
      "affs": [
        36
      ],
      "name": "Ming‐Lung Yu",
      "orcid": "0000-0001-8145-1900"
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    {
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        37
      ],
      "name": "Wenhong Zhang",
      "orcid": "0000-0002-9165-3212"
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    {
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        38
      ],
      "name": "Hui Zhuang"
    },
    {
      "affs": [
        39
      ],
      "name": "Ching‐Lung Lai",
      "orcid": "0000-0002-5927-2436"
    },
    {
      "name": "Masao Omata"
    },
    {
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        1
      ],
      "name": "Shiv Kumar Sarin",
      "orcid": "0000-0002-0544-5610"
    },
    {
      "name": "George K.K. Lau",
      "orcid": "0000-0002-8928-3769"
    },
    {
      "name": "APASL Viral Elimination Taskforce"
    }
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  "bibtex": "https://research.draconitic.com/paper/1jyc107r5myd2.bib",
  "cited_by": 10,
  "doi": "10.1007/s12072-026-11108-1",
  "fulltext_url": null,
  "id": "1jyc107r5myd2",
  "issns": [
    "1936-0533",
    "1936-0541"
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  "landing_url": "https://doi.org/10.1007/s12072-026-11108-1",
  "language": "en",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
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  "native_subjects": [
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      "2713|Hepatitis B Virus Studies"
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  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s12072-026-11108-1.pdf",
  "pmcid": null,
  "pmid": "42365189",
  "published": "2026-06-27",
  "publisher": "Springer Science+Business Media",
  "ris": "https://research.draconitic.com/paper/1jyc107r5myd2.ris",
  "sources": [
    {
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  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2713|Hepatitis B Virus Studies",
      "subfield": "epidemiology-public-health"
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  "title": "APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update",
  "title_text": "APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update",
  "type": "peer-reviewed",
  "updated_at": "2026-11-02T13:20:46Z",
  "url": "https://research.draconitic.com/paper/1jyc107r5myd2",
  "venue": "Hepatology International",
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}