{
  "abstract": "Purpose: The Multinational Association of Supportive Care in Cancer (MASCC) is internationally recognized for developing evidence-based Clinical Practice Guidelines (CPGs) for managing cancer or treatment–related toxicities, but their uptake remains uncertain. This study aimed to evaluate global awareness, utilization, and perceptions of MASCC CPGs, to inform strategies to enhance future updates and promote their implementation.\n\nMethods: An international online survey was distributed via the MASCC platform between February and March 2025 to healthcare professionals specialized in supportive care in cancer. The survey included both closed- and open-ended questions addressing awareness, usage, perceived strengths and limitations, implementation challenges, and suggestions for improvement.\n\nResults: A total of 423 responses were received, 264 (63%) from MASCC members. Participants represented all world regions, with 271 (65%) having 11–20 or more years of clinical experience. Overall, 302 (78%) reported routinely using MASCC CPGs in the management of cancer or treatment-related toxicities. Even among non-members, MASCC CPGs were cited as the most frequently used guidelines compared with other sources. The mucositis and antiemetics CPGs were the most recognized and applied. Key facilitators included the guidelines’ strong evidence and multidisciplinary development. Reported barriers included limited availability or high cost of recommended interventions. Respondents suggested improvements related to the timing of updates, dissemination strategies, and the inclusion of patient-facing guidelines.\n\nConclusions: MASCC CPGs are widely recognized and valued globally, yet implementation remains variable. Targeted efforts to address resource constraints and enhance dissemination may strengthen their global awareness and implementation.\n\nSupplementary information: The online version contains supplementary material available at https://doi.org/10.1007/s00520-026-11388-1.",
  "abstract_shown": true,
  "affiliations": [
    "Technion Israel Institute of Technology, Faculty of Medicine, Technion City, Haifa, 3200003 Israel",
    "Department of Oral and Maxillofacial Surgery, Rambam Health Care Campus, Haifa, Israel",
    "School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy",
    "Department of Hematology, Radboud University Medical Centre, Nijmegen, The Netherlands",
    "Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy",
    "School of Pharmacy and Biomedical Science, Adelaide University, Adelaide, Australia",
    "Instituto de Ensino E Pesquisa, Hospital Sírio-Libanês, São Paulo, Brazil",
    "Flinders LiveWell Cancer Research Centre, Caring Futures Institute, College of Health and Enablement, Flinders University, Adelaide, SA Australia",
    "School of Pharmacy, Faculty of Medicine, the Chinese University of Hong Kong, Shatin, Hong Kong SAR Hong Kong",
    "School of Medicine, Trinity College Dublin, Dublin, Ireland",
    "Palliative Medicine, Division of Oncology Supportive Care, Levine Cancer Institute, Charlotte, NC USA",
    "Oral Medicine, Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY USA",
    "Cedars Sinai National Medical Center Los Angeles, Los Angeles, CA USA",
    "Cancer Dentistry, Division of Otolaryngology and Head and Neck Surgery, City of Hope, Duarte, CA USA",
    "The Department of Gastroenterology, Nottingham Digestive Diseases Centre, Derby Road, Nottingham, NG7 2UH UK",
    "Division of Oncology, Children’s Hospital of Philadelphia, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA USA",
    "Human Performance Research Centre, INSIGHT Research Institute, University of Technology Sydney (UTS), Sydney, NSW Australia",
    "Department of Pharmacy, Gifu University Hospital, 1-1 Yanagido, Gifu, 501-1194 Japan",
    "Cancer Center, Gifu University Hospital, 1-1 Yanagido, Gifu, 501-1194 Japan",
    "Centre for Health Services Research in Cancer, Australian Cancer Survivorship Centre, and Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria Australia",
    "Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria Australia",
    "Adelaide University, Adelaide, Australia",
    "Department of Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, MD 21201 USA",
    "Australian Research Centre for Cancer Survivorship, UNSW Medicine & Health, UNSW Sydney, in partnership with Cancer Council NSW, Sydney, Australia",
    "Flinders University, Adelaide, Australia",
    "School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK",
    "Haematology and Bone Marrow Transplant Cancer Care Services, Royal Brisbane and Women’s Hospital, Herston, Queensland Australia",
    "Vanderbilt University Medical Center, Nashville, TN USA",
    "Pharmacy Department, Royal Brisbane and Women’s Hospital, Herston, Queensland Australia",
    "Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO USA",
    "Divisions of Oral Medicine, Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, MA USA",
    "Biomodels. LLC and Primary Endpoint Solutions, LLC, Waltham, MA USA",
    "Oncology Department, Veterans Hospital (417 NIMTS), Athens, Greece",
    "Henry Dunant Hospital Center, Athens, Greece",
    "Institute for Health Transformation, Quality and Patient Safety, Deakin University, Geelong, Victoria Australia",
    "Catharina Hospital, Eindhoven, The Netherlands",
    "Santeon, Utrecht, The Netherlands",
    "School of Pharmacy and Biomedical Science, College of Health, Adelaide University, Adelaide, South Australia Australia",
    "Supportive Oncology Research Group, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia Australia",
    "Department of Biomedical Sciences, Humanitas University, IRCCS Humanitas Research Hospital, Milan, Italy"
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 31,
  "authors": [
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      "name": "Ragda Abdalla-Aslan",
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      "name": "Paola Alberti"
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      "name": "Joel Epstein"
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      "name": "Darren Fernandes"
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      "name": "Michael Jefford"
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      "name": "Daniel Peter Johnstone"
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      "name": "Amber S. Kleckner"
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      "name": "Bogda Koczwara"
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      "name": "Enrique Soto-Perez-de-Celis"
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      "name": "Stephen Sonis"
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      "name": "Nikolaos Tsoukalas"
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      "name": "Anna Ugalde"
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      "name": "Corina van den Hurk"
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      "name": "Hannah Rose Wardill"
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    {
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        39
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      "name": "Paolo Bossi"
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  "bibtex": "https://research.draconitic.com/paper/1k6zaqzzgjth9.bib",
  "cited_by": 0,
  "doi": "10.1007/s00520-026-11388-1",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13736418/",
  "id": "1k6zaqzzgjth9",
  "issns": [
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    "1433-7339"
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  "landing_url": "https://doi.org/10.1007/s00520-026-11388-1",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Research"
    ],
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      "openalex",
      "2739|Clinical practice guidelines implementation"
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  "openalex": "W7225275070",
  "pdf_url": "https://link.springer.com/content/pdf/10.1007/s00520-026-11388-1.pdf",
  "pmcid": "PMC13736418",
  "pmid": "42980825",
  "published": "2026-11-04",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1k6zaqzzgjth9.ris",
  "sources": [
    {
      "first_seen": "2026-11-09T12:21:52Z",
      "native_id": "PMC13736418",
      "source": "pmc",
      "url": "https://doi.org/10.1007/s00520-026-11388-1"
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  "subjects": [
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      "field": "medicine",
      "origin": "openalex:2739|Clinical practice guidelines implementation",
      "subfield": "epidemiology-public-health"
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  "title": "Global perspectives on MASCC clinical practice guidelines: awareness, implementation and insights to inform future updates",
  "title_text": "Global perspectives on MASCC clinical practice guidelines: awareness, implementation and insights to inform future updates",
  "type": "peer-reviewed",
  "updated_at": "2026-11-09T12:21:52Z",
  "url": "https://research.draconitic.com/paper/1k6zaqzzgjth9",
  "venue": "Supportive Care in Cancer",
  "versions": []
}