{
  "abstract": "•The prostate harbors a diverse and previously undercharacterized microbial ecosystem with species-level resolution.•Prostate cancer (PCa) patients exhibit higher microbial richness and α-diversity in prostate tissue than non PCa patients.•Distinct microbial communities are observed across prostate, urinary, and rectal niches, independent of cancer status.•Cutibacterium acnes is enriched in PCa patients' biopsies, Lactobacillus reuteri in non-PCa patients' biopsies.•Findings highlight potential prostate-associated pathobionts and protective commensalssignatures.",
  "abstract_shown": true,
  "affiliations": [
    "Laboratoire de Bactériologie du CHU de Nice, Hôpital Archet 2, Nice, France.",
    "Inserm U1065, Centre Méditerranéen de Médecine Moléculaire, Équipe 6, Nice, France.",
    "Université Cote d'Azur, Faculté de Médecine de Nice, Nice, France.",
    "Délégation à la Recherche Clinique et à l'Innovation du CHU de Nice, Hôpital de Cimiez, Nice, France.",
    "Service d'Urologie du CHU de Nîmes, Hôpital Carémeau, Nîmes, France.",
    "Laboratoire de Microbiologie du CHU de Nîmes, Hôpital Carémeau, Nîmes, France.",
    "Service d'Urologie du CHU de Tours, Hôpital Bretonneau, Tours, France.",
    "Laboratoire de Bactériologie du CHU de Tours, Hôpital Bretonneau, Tours, France.",
    "Service d'Urologie de l'APHM, Hôpital la Conception, Marseille, France.",
    "Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.",
    "Service d'Urologie du CH de Cannes, Hôpital Simone Veil, Cannes, France.",
    "Laboratoire de Biologie du CH de Cannes, Hôpital Simone Veil, Cannes, France.",
    "Service d'Urologie du CH de Menton, Hôpital La Palmosa, Menton, France.",
    "Service d'Urologie du CHU de Nice, Hôpital Pasteur 2, Nice, France."
  ],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 24,
  "authors": [
    {
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        0,
        1,
        2
      ],
      "name": "R Lotte"
    },
    {
      "affs": [
        0
      ],
      "name": "A Gaudart"
    },
    {
      "affs": [
        3
      ],
      "name": "C Cruzel"
    },
    {
      "affs": [
        4
      ],
      "name": "S Droupy"
    },
    {
      "affs": [
        5
      ],
      "name": "J P Lavigne"
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    {
      "affs": [
        6
      ],
      "name": "F Bruyère"
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    {
      "affs": [
        7
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      "name": "P Lanotte"
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    {
      "affs": [
        8
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      "name": "E Lechevallier"
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    {
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        9
      ],
      "name": "G Dubourg"
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    {
      "affs": [
        9
      ],
      "name": "P E Fournier"
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    {
      "affs": [
        10
      ],
      "name": "R Haider"
    },
    {
      "affs": [
        11
      ],
      "name": "L Lotte"
    },
    {
      "affs": [
        12
      ],
      "name": "K Youssef"
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    {
      "affs": [
        0
      ],
      "name": "A Emery"
    },
    {
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        0
      ],
      "name": "R Madany"
    },
    {
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        0
      ],
      "name": "M Payen"
    },
    {
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        0
      ],
      "name": "L Pfauwadel"
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    {
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        13
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      "name": "B Tibi"
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    {
      "affs": [
        13
      ],
      "name": "Y Ahallal"
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    {
      "affs": [
        13
      ],
      "name": "S Zouari"
    },
    {
      "affs": [
        13
      ],
      "name": "I Bentellis"
    },
    {
      "affs": [
        3
      ],
      "name": "E Fontas"
    },
    {
      "affs": [
        13
      ],
      "name": "M Durand"
    },
    {
      "affs": [
        0,
        1,
        2
      ],
      "name": "R Ruimy"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1ntjbag3bypaa.bib",
  "cited_by": 0,
  "doi": "10.1016/j.nmni.2026.101862",
  "fulltext_url": "https://europepmc.org/articles/PMC13682004",
  "id": "1ntjbag3bypaa",
  "issns": [
    "2052-2975"
  ],
  "landing_url": "https://europepmc.org/article/MED/42904090",
  "language": "eng",
  "licence": "CC-BY",
  "licence_label": "CC BY",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1312|Gut microbiota and health"
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  "openalex": "W7221029359",
  "pdf_url": "https://europepmc.org/articles/PMC13682004?pdf=render",
  "pmcid": "PMC13682004",
  "pmid": "42904090",
  "published": "2026-10-08",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1ntjbag3bypaa.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:19:53Z",
      "native_id": "MED:42904090",
      "source": "europepmc",
      "url": "https://europepmc.org/article/MED/42904090"
    }
  ],
  "subjects": [
    {
      "field": "biochemistry",
      "origin": "openalex:1312|Gut microbiota and health",
      "subfield": "molecular-biology"
    }
  ],
  "title": "Prostate tissue microbiota dysbiosis associated with prostate cancer: results from the MICROPROSTK multicenter study.",
  "title_text": "Prostate tissue microbiota dysbiosis associated with prostate cancer: results from the MICROPROSTK multicenter study.",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:19:53Z",
  "url": "https://research.draconitic.com/paper/1ntjbag3bypaa",
  "venue": "New microbes and new infections",
  "versions": []
}