{
  "abstract": "BACKGROUND: This study compared changes in percentage atheroma volume (PAV) using an end-diastolic (ED) intravascular ultrasound (IVUS) segmentation approach vs. the conventional 1-mm interval analysis in serial IVUS data from the PACMAN-AMI trial. METHODS AND RESULTS: , respectively [P=0.823]; PAV: 1.29% vs. 1.25%, respectively [P=0.911]). Biomarker correlations with TAV and PAV changes did not differ between approaches. CONCLUSIONS: ED- and 1-mm-based analyses demonstrated comparable treatment effects of alirocumab on plaque regression in PACMAN-AMI. These findings support the use of the less time-consuming 1-mm segmentation method in serial IVUS studies.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 18,
  "authors": [
    {
      "name": "Nathan Angelo Lecaros Yap"
    },
    {
      "name": "Christos V. Bourantas"
    },
    {
      "name": "Sylvain Losdat"
    },
    {
      "name": "Nathaniel Yu Jian Ng"
    },
    {
      "name": "Jonas Häner"
    },
    {
      "name": "Ibrahim Halil Tanboga"
    },
    {
      "name": "Tatsuhiko Otsuka"
    },
    {
      "name": "Yasushi Ueki"
    },
    {
      "name": "Andreas Baumbach"
    },
    {
      "name": "Anthony Mathur"
    },
    {
      "name": "Ryota Kakizaki"
    },
    {
      "name": "Ernest Spitzer"
    },
    {
      "name": "Jouke Dijkstra"
    },
    {
      "name": "Thomas Engstrøm"
    },
    {
      "name": "David Spirk"
    },
    {
      "name": "Irene Lang"
    },
    {
      "name": "Konstantinos C. Koskinas"
    },
    {
      "name": "Lorenz Räber"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1nzypxedt8nss.bib",
  "cited_by": 2,
  "doi": "10.1253/circj.cj-25-0590",
  "fulltext_url": "https://www.jstage.jst.go.jp/article/circj/90/8/90_CJ-25-0590/_article",
  "id": "1nzypxedt8nss",
  "issns": [
    "1347-4820",
    "1346-9843"
  ],
  "landing_url": "https://www.jstage.jst.go.jp/article/circj/90/8/90_CJ-25-0590/_article",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "jstage-journal",
      "medicine/cardiovascular"
    ],
    [
      "openalex",
      "2746|Coronary Interventions and Diagnostics"
    ]
  ],
  "openalex": "W7133350789",
  "pdf_url": "https://www.jstage.jst.go.jp/article/circj/advpub/0/advpub_CJ-25-0590/_pdf",
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-24",
  "publisher": null,
  "ris": "https://research.draconitic.com/paper/1nzypxedt8nss.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:24Z",
      "native_id": "10.1253/circj.cj-25-0590",
      "source": "jstage",
      "url": "https://www.jstage.jst.go.jp/article/circj/90/8/90_CJ-25-0590/_article"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2746|Coronary Interventions and Diagnostics",
      "subfield": "surgery"
    }
  ],
  "title": "Comparison of Atheroma Burden Changes Using Conventional vs. End-Diastolic Intravascular Ultrasound Segmentation ― Post Hoc Analysis of the PACMAN-AMI Study ―",
  "title_text": "Comparison of Atheroma Burden Changes Using Conventional vs. End-Diastolic Intravascular Ultrasound Segmentation ― Post Hoc Analysis of the PACMAN-AMI Study ―",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T12:17:24Z",
  "url": "https://research.draconitic.com/paper/1nzypxedt8nss",
  "venue": "Circulation Journal",
  "versions": []
}