{
  "abstract": "We report a method to prepare alkenes through the base-promoted oxidative desaturation of alkylarenes and related weakly acidic functional groups. This process operates via a tandem deprotonative-halogenation and elimination sequence using haloarene halogen-transfer reagents. The use of potassium tert-butoxide with haloarene oxidants provides a simple means to desaturate a broad range of alkylarenes, acids, esters, and amides, as well as to aromatize saturated heterocycles. A critical feature for reaction success is the generation of tert-butanol from the tert-butoxide base which buffers the reaction solution to prevent anionic alkene polymerization. The utility of this approach is enhanced by its direct sequencing with additional base-promoted processes, such as hydrofunctionalization, to access formal homobenzylic C–H functionalization products.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Chemistry",
    "Colorado State University"
  ],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "Eve L. Sugg"
    },
    {
      "name": "Garrett A. Hoteling"
    },
    {
      "name": "Viet Ngo"
    },
    {
      "affs": [
        0,
        1
      ],
      "name": "Jeffrey S. Bandar",
      "orcid": "0000-0001-5418-3082"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1p39pdfaxkvs9.bib",
  "cited_by": 0,
  "doi": "10.26434/chemrxiv.15009162/v1",
  "fulltext_url": null,
  "id": "1p39pdfaxkvs9",
  "issns": [],
  "landing_url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009162/v1",
  "language": null,
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "openalex",
      "1605|Catalytic C–H Functionalization Methods"
    ]
  ],
  "openalex": "W7213942556",
  "pdf_url": "https://chemrxiv.org/doi/pdf/10.26434/chemrxiv.15009162/v1",
  "pmcid": null,
  "pmid": null,
  "published": "2026-09-21",
  "publisher": "American Chemical Society (ACS)",
  "ris": "https://research.draconitic.com/paper/1p39pdfaxkvs9.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T12:17:19Z",
      "native_id": "10.26434/chemrxiv.15009162",
      "source": "chemrxiv",
      "url": "https://chemrxiv.org/doi/full/10.26434/chemrxiv.15009162/v1"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:1605|Catalytic C–H Functionalization Methods",
      "subfield": "organic"
    }
  ],
  "title": "Direct Alkylarene Desaturation via Base-Promoted Halogen Transfer",
  "title_text": "Direct Alkylarene Desaturation via Base-Promoted Halogen Transfer",
  "type": "preprint",
  "updated_at": "2026-10-30T12:17:19Z",
  "url": "https://research.draconitic.com/paper/1p39pdfaxkvs9",
  "venue": "ChemRxiv",
  "versions": []
}