{
  "abstract": "PURPOSE: This study aimed to evaluate the choroidal vascularity index (CVI) in patients with nonproliferative and proliferative macular telangiectasia type 2 (MacTel-2) compared to healthy controls, assess the impact of ellipsoid zone (EZ) disruption on CVI, and determine whether CVI measurements vary with different binarization areas. MATERIALS AND METHODS: CVIs from MacTel-2 eyes were compared to those of healthy controls. MacTel-2 eyes were categorized as proliferative or nonproliferative and further subdivided by the presence or absence of EZ disruption. CVI was measured in three regions: 1500 µm, 4000 µm, and the total macular choroidal area (TCA). Statistical analyses included paired samples t-tests, independent samples t-tests, and Mann–Whitney U-tests. P < 0.05 was considered statistically significant. RESULTS: This study included 90 eyes each from MacTel-2 patients and healthy controls. CVIs did not significantly differ between eyes with and without EZ disruption in either MacTel-2 group (P > 0.05). CVIs beneath EZ-disrupted areas were also comparable to intact zones (P > 0.05). No significant CVI difference was observed between nonproliferative and proliferative MacTel-2 eyes (P > 0.1). However, both the groups had significantly lower CVIs than healthy controls across all measured areas (P < 0.001 for nonproliferative and P < 0.05 for proliferative). CVI values were consistent across all binarization areas (P > 0.1). CONCLUSION: EZ disruption does not affect CVI. CVIs were similar in nonproliferative and proliferative MacTel-2, both lower than in healthy eyes. CVI also remained consistent across different binarization areas, confirming its reliability regardless of area size.",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": null,
  "arxiv": null,
  "author_total": 4,
  "authors": [
    {
      "name": "Zeynep Eylul Ercan"
    },
    {
      "name": "Gulsah Gokgoz"
    },
    {
      "name": "İmren Akkoyun"
    },
    {
      "name": "Gursel Yilmaz"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1qyzqz4fykx7w.bib",
  "cited_by": 0,
  "doi": "10.4103/tjo.tjo-d-25-00092",
  "fulltext_url": "https://www.ovid.com/jnls/tjop/fulltext/10.4103/tjo.tjo-d-25-00092~choroidal-vascularity-index-changes-in-proliferative-and",
  "id": "1qyzqz4fykx7w",
  "issns": [
    "2211-5056",
    "2211-5072"
  ],
  "landing_url": "https://doi.org/10.4103/tjo.tjo-d-25-00092",
  "language": "en",
  "licence": "CC-BY-NC-ND",
  "licence_label": "CC BY-NC-ND",
  "licence_source": "journal",
  "licence_url": "https://creativecommons.org/licenses/by-nc-nd/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "lcc",
      "RE1-994"
    ],
    [
      "openalex",
      "2731|Retinal Diseases and Treatments"
    ]
  ],
  "openalex": "W4415250419",
  "pdf_url": null,
  "pmcid": null,
  "pmid": null,
  "published": "2026-07-01",
  "publisher": "Wolters Kluwer Medknow Publications",
  "ris": "https://research.draconitic.com/paper/1qyzqz4fykx7w.ris",
  "sources": [
    {
      "first_seen": "2026-10-30T13:43:57Z",
      "native_id": "998ef0e937e8444090e51613567ca782",
      "source": "doaj",
      "url": "https://doi.org/10.4103/tjo.tjo-d-25-00092"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2731|Retinal Diseases and Treatments",
      "subfield": "general"
    }
  ],
  "title": "Choroidal vascularity index changes in proliferative and nonproliferative macular telangiectasia type 2",
  "title_text": "Choroidal vascularity index changes in proliferative and nonproliferative macular telangiectasia type 2",
  "type": "peer-reviewed",
  "updated_at": "2026-10-30T13:43:57Z",
  "url": "https://research.draconitic.com/paper/1qyzqz4fykx7w",
  "venue": "Taiwan Journal of Ophthalmology",
  "versions": []
}