{
  "abstract": "色谱是一种重要的分离分析技术，广泛应用于环境监测、生命科学、食品安全和药物分析等领域。作为色谱分离技术的核心，色谱固定相对分离性能有着决定性作用。以硅胶为基质的固定相尽管已被广泛应用于色谱分离，但硅胶基质存在制备工艺复杂、传质阻力大、pH适用范围窄等缺点，严重阻碍其深入应用。因此，开发兼具高化学稳定性和高分离性能的新型固定相以满足不同场景的分离需求，始终是色谱分析领域的研究热点。共价有机框架（COFs）作为一类新兴的多孔晶态材料，具有比表面积大、孔道结构规整、高化学/热稳定性等显著优势，不仅有望克服上述问题，还可通过对孔道功能化修饰实现对目标分析物的精准识别，因而被认为是构建高性能色谱固定相的理想材料。本文系统述评了近两年来COFs在气相色谱与液相色谱固定相应用方面的研究进展，重点围绕COFs材料的结构设计与性能调控，阐述其在有机化合物广谱分离、位置异构体分离以及手性化合物拆分等方面的应用与分离机制。在此基础上，结合当前研究现状与存在问题，对COFs基色谱固定相的发展方向与应用前景进行了分析与展望。",
  "abstract_shown": true,
  "affiliations": [],
  "article_type": "research article",
  "arxiv": null,
  "author_total": 7,
  "authors": [
    {
      "name": "Kaixing LUO"
    },
    {
      "name": "Ying SUN"
    },
    {
      "name": "Qiuting ZHANG"
    },
    {
      "name": "Lusha WU"
    },
    {
      "name": "Jiamin SONG"
    },
    {
      "name": "Yanhui ZHONG"
    },
    {
      "name": "Zian LIN"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1vczvehy5yzn6.bib",
  "cited_by": 0,
  "doi": "10.3724/sp.j.1123.2026.01026",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13729048/",
  "id": "1vczvehy5yzn6",
  "issns": [
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    "1872-2059"
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  "landing_url": "https://doi.org/10.3724/sp.j.1123.2026.01026",
  "language": "zh",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Mini-Reviews"
    ],
    [
      "heading",
      "O658"
    ],
    [
      "heading",
      "a"
    ],
    [
      "openalex",
      "2505|Covalent Organic Framework Applications"
    ]
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  "openalex": "W7225153308",
  "pdf_url": null,
  "pmcid": "PMC13729048",
  "pmid": "42973224",
  "published": "2026-11-07",
  "publisher": "Editorial Office of Chinese Journal of Chromatography",
  "ris": "https://research.draconitic.com/paper/1vczvehy5yzn6.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:21:53Z",
      "native_id": "PMC13729048",
      "source": "pmc",
      "url": "https://doi.org/10.3724/sp.j.1123.2026.01026"
    }
  ],
  "subjects": [
    {
      "field": "chemistry",
      "origin": "openalex:2505|Covalent Organic Framework Applications",
      "subfield": "materials-polymers"
    }
  ],
  "title": "共价有机框架色谱固定相研究新进展",
  "title_text": "共价有机框架色谱固定相研究新进展",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:21:53Z",
  "url": "https://research.draconitic.com/paper/1vczvehy5yzn6",
  "venue": "Chinese Journal of Chromatography",
  "versions": []
}