{
  "abstract": "Introduction/background: Intraosseous microcystic meningioma is an exceptionally rare clinical entity, representing a diagnostic challenge due to its atypical osteolytic presentation and specific histological features. This case is unique because it occurs in a 43-year-old patient—younger than the reported median age—and highlights specific MRI \"shine-through\" effects that can assist in preoperative differentiation from aggressive bone malignancies.\n\nCase presentation: A 43-year-old woman presented with a six-month history of intermittent parietal pain. Imaging revealed a 1.9 × 0.9 cm osteolytic defect in the right frontal bone with internal septations. MRI showed T2-hyperintensity and heterogeneous enhancement, but no restricted diffusion on ADC maps. The patient underwent gross total resection with dural repair and titanium mesh reconstruction. Histopathology confirmed a WHO Grade I microcystic meningioma, positive for EMA, SSTR2, and D2-40.\n\nConclusion: The main \"take-away\" is that intraosseous microcystic meningioma should be considered in the differential diagnosis of solitary osteolytic skull lesions. Multi-parametric MRI, specifically the absence of restricted diffusion despite high DWI signal (T2 shine-through), is a key indicator of this benign, fluid-rich subtype.",
  "abstract_shown": true,
  "affiliations": [
    "Department of Radiology, Zhejiang University School of Medicine First Affiliated Hospital, 79 Qingchun Road, Hangzhou, 310003 Zhejiang China",
    "Department of Pathology, Zhejiang University School of Medicine First Affiliated Hospital, 79 Qingchun Road, Hangzhou, 310003 Zhejiang China"
  ],
  "article_type": "case report",
  "arxiv": null,
  "author_total": 3,
  "authors": [
    {
      "affs": [
        0
      ],
      "name": "Haijuan Teng",
      "orcid": "0000-0002-9663-6366"
    },
    {
      "affs": [
        1
      ],
      "name": "Xuejie Li",
      "orcid": "0009-0007-8341-5998"
    },
    {
      "affs": [
        0
      ],
      "name": "Xiaoxia Zhang",
      "orcid": "0009-0008-3879-9109"
    }
  ],
  "bibtex": "https://research.draconitic.com/paper/1wq1zn5yrvbh0.bib",
  "cited_by": 0,
  "doi": "10.1186/s13256-026-06354-8",
  "fulltext_url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC13729414/",
  "id": "1wq1zn5yrvbh0",
  "issns": [
    "1752-1947"
  ],
  "landing_url": "https://doi.org/10.1186/s13256-026-06354-8",
  "language": "en",
  "licence": "CC-BY-4.0",
  "licence_label": "CC BY 4.0",
  "licence_source": "article",
  "licence_url": "https://creativecommons.org/licenses/by/4.0/",
  "metadata_licence": null,
  "native_subjects": [
    [
      "heading",
      "Case Report"
    ],
    [
      "openalex",
      "2728|Meningioma and schwannoma management"
    ]
  ],
  "openalex": "W7197022392",
  "pdf_url": null,
  "pmcid": "PMC13729414",
  "pmid": "42977975",
  "published": "2026-08-06",
  "publisher": "BMC",
  "ris": "https://research.draconitic.com/paper/1wq1zn5yrvbh0.ris",
  "sources": [
    {
      "first_seen": "2026-11-07T12:22:10Z",
      "native_id": "PMC13729414",
      "source": "pmc",
      "url": "https://doi.org/10.1186/s13256-026-06354-8"
    }
  ],
  "subjects": [
    {
      "field": "medicine",
      "origin": "openalex:2728|Meningioma and schwannoma management",
      "subfield": "neurology"
    }
  ],
  "title": "Rare case of dual lesion: intraosseous microcystic meningioma – case report and review of literature",
  "title_text": "Rare case of dual lesion: intraosseous microcystic meningioma – case report and review of literature",
  "type": "peer-reviewed",
  "updated_at": "2026-11-07T12:22:10Z",
  "url": "https://research.draconitic.com/paper/1wq1zn5yrvbh0",
  "venue": "Journal of Medical Case Reports",
  "versions": []
}